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AAT Bioquest

Why does specificity in chromatography matter?

Posted May 8, 2024


Answer

Specificity in chromatography ensures the precise identification of the target substance. It also ensures that the analysis gives accurate results regarding the quantity or strength of the substance being analyzed. Specificity also allows chromatographic methods to accurately quantify impurities in a sample. In quantitative assays, specificity ensures that the chromatographic method provides exact results for the concentration or content of the analyte in the sample.

Additional resources

Validation of the Specificity of Chromatographic Methods: Key Points and Practical Recommendations

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