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AAT Bioquest

What's the significance of equilibrium potential?

Posted July 3, 2024


Answer

Equilibrium potential is significant because it helps determine the direction and magnitude of ion movement when channels for that ion open. A positive equilibrium potential is necessary to prevent Sodium (Na+) ions from the extracellular fluid entering the cell. Conversely, a negative equilibrium potential is necessary to prevent K+ ions from leaving the cell and to stop Chloride (Cl-) ions from entering the cell.

Additional resources

ELECTROCHEMICAL THEORY | Kinetics

Cell/Cytoplasmic Membrane Potential Activity & Analysis

Screen Quest™ Membrane Potential Assay Kit *Red Fluorescence*