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AAT Bioquest

What is the significance of reduced representation sequencing?

Posted April 26, 2024


Answer

Reduced representation sequencing (RRS) sequences only a fraction of the genome (typically CpG-rich regions) which significantly simplifies the process and resulting dataset compared to whole-genome approaches. This also makes it more cost-effective. This approach is valuable for various applications in population genetics, molecular breeding, and other research fields. It also enables the development of molecular markers, construction of genetic maps and the mapping of quantitative trait loci (QTL).

Additional resources

Reduced representation approaches produce similar results to whole genome sequencing for some common phylogeographic analyses

Next Generation Sequencing (NGS)

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