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AAT Bioquest

What is a LAMP test?

Posted June 17, 2022


Answer

The LAMP (loop-mediated isothermal amplification) test is a form of testing that involves replicating or amplifying small fragments of genetic material at a constant temperature. The real-time loop-mediated amplification method that LAMP uses to amplify the genetic material in a sample makes it faster and more cost effective than a PCR (polymerase chain reaction) test. In the LAMP test, the fragments of DNA are amplified at one temperature only, which speeds up the reaction time. This method of amplifying DNA at one temperature is what sets the LAMP test apart from the more conventional PCR test, which uses temperature cycling for DNA replication. LAMP tests have been designed to detect RNA and DNA targets from a variety of sources. Recently, they have been very popular and successful in detecting covid as well as foodborne pathogens.

Additional resources

Loop-mediated isothermal amplification (LAMP): a versatile technique for detection of micro-organisms

Coronavirus (SARS-CoV-2)

LAMP Green™ *50X DMSO Solution*