logo
AAT Bioquest

What criteria should I use for the selection of capillary electrophoresis (CE) or liquid chromatography (LC) as separation and analysis technique?

Posted May 29, 2024


Answer

One criteria for selecting CE over LC is when analytes are primarily charged or ionic. Another criteria is when minimal sample consumption is required. CE typically requires minimal sample volumes for analysis, making it suitable for applications where sample availability is limited. Another criteria is that CE typically offers faster analysis times compared to LC. The separation process in CE is driven by an electric field, enabling rapid migration. Lastly, CE is preferred over LC when high separation efficiency is necessary for small molecules.

Additional resources

An Introduction to Capillary Electrophoresis: Theory, Practice and Applications

Affinity Purification

MegaWox™ polyHRP-Protein A Conjugate