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AAT Bioquest

What are the possible solutions to noisy sequences?

Posted August 30, 2024


Answer

Noisy sequence refers to unwanted signals or errors that occur during the sequencing process. These can cause the data to be wrongly interpreted. Possible solutions to noisy sequences include: 

  • Increasing template concentration
  • Choosing another primer
  • Redo DNA prep
  • Requesting alternative sequencing program
Additional resources

The effect of background noise and its removal on the analysis of single-cell expression data

Sanger Sequencing

Gene Expression Analysis & Genotyping

MagaDye™ 535-ddGTP