What are the differences between T helper and T cytotoxic cells?
Posted August 24, 2023
Basis of differentiation |
T helper cells |
T cytotoxic cells |
Definition |
Are a type of immune cell that plays a supportive role in the immune system by recognizing foreign antigens and secreting cytokines that activate T and B cells |
Are a type of immune cell that is capable of directly killing certain cells including tumor cells and virus infected cells directly by destroying the cell membranes |
Types of T cell receptor (TCR) on cell membrane |
CD4 receptors |
CD8 receptors |
Antigen presentation |
Dendritic cells, macrophages, and neutrophils |
Virus-infected cells and tumor cells |
Major Histocompatibility Complex (MHC) molecules |
CD4 receptors present on the cell membrane can recognize antigens presented with MHC class II molecules |
CD8 receptors present on the cell membrane can recognize antigens presented with MHC class I molecules |
Has the ability to kill pathogen directly |
No |
Yes |
Role |
Secretion of cytokines that help to regulate other cells in the immune system and present antigens to the B cells |
Directly destroy virus-infected cells and tumor cells |
Helper T Cells and Lymphocyte Activation