What are the differences between progenitor cells and stem cells?
Posted November 6, 2023
Basis of differentiation |
Progenitor cells |
Stem cells |
Definition |
These cells are unipotent or multipotent stem cells which originate from stem cells; they differentiate to form specialized cell types |
Are undifferentiated cells of a multicellular organism which that able to infinitely multiply into more cells of the same type |
Cellular potency |
Are either unipotent or oligopotent |
Can either be multipotent, pluripotent, or totipotent |
Degree of differentiation |
Are somewhat differentiated |
Are completely undifferentiated |
Self-renewal |
Have a limited self-renewal ability |
Are easily able to undergo self-renewal and divide into identical stem cells |
Location |
Found in specific tissues and organs |
Found in many different types of tissues and organs throughout the body |
Origin |
Are derived from stem cells which then differentiate again to form specialized cell types |
Originate from embryos or adult tissues |
Function |
Their primary function is to replenish dead or damaged cells |
Their function is to regenerate damaged tissues and organs |