What are the differences between mitosis and meiosis?
Posted March 15, 2023
Basis of differentiation |
Mitosis |
Meiosis |
Definition |
A type of cell division that results in two identical daughter cells having the same number of chromosomes as the parent cell |
A type of cell division that results in four daughter cells each with half the number of chromosomes as its parent cell (for production of gametes) |
Cell division |
During mitosis, a somatic cell divides once, cytokinesis occurs at the end of telophase |
A reproductive cell divides twice, cytokinesis occurs at the end of telophase I and II |
Daughter cell number |
Mitosis produces 2 daughter cells, each cell is diploid containing the same number of chromosomes |
Meiosis produces 4 daughter cells, each cell is haploid containing half the number of chromosomes as the parent cell |
Length of prophase |
During prophase in mitosis, a cell spends less time in prophase than a cell in prophase I of meiosis |
Prophase I has five stages and lasts longer than prophase of mitosis. The five stages of meiotic prophase I are leptotene, zygotene, pachytene, diplotene, and diakinesis. |
Genetic composition/variation |
The resulting daughter cells in mitosis are genetically identical (no recombination or crossing over occurs and thus no genetic variation occurs) |
The resulting daughter cells have different combinations of genes. Genetic recombination occurs due to the random segregation of homologous chromosomes into different cells and through crossing over (genetic variation increases |
Chromosome alignment in metaphase |
Sister chromatids align at the metaphase plate in mitosis |
Tetrads align at the metaphase plate in metaphase I |
Tetrad formation |
Tetrad formation does not occur ` |
In prophase I, homologous chromosome pairs line up together forming tetrads (two sets of sister chromatids) |
Chromosome separation |
During anaphase, sister chromatids separate and migrate toward opposite poles of the cell |
Homologous chromosomes migrate toward the opposite poles of the cell during anaphase I (sister chromatids don’t separate in anaphase I) |
Steps |
Has 6 steps total |
Has 9 steps in total |
Occurrence |
Occurs in somatic cells |
Occurs in germ cells |
Chromosome number |
Chromosome number remains the same |
Chromosome number is halved in each daughter cell |
Purpose |
The purpose of mitosis is cell proliferation |
The purpose of meiosis is sexual reproduction |
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Cell Meter™ Fluorimetric Live Cell Cycle Assay Kit *Green Fluorescence Optimized for Flow Cytometry*