What are the differences between chromatin and chromatids?
Posted July 28, 2023
Basis of differentiation |
Chromatin |
Chromatids |
Definition |
Chromatin is the readily stainable substance of a cell nucleus, consisting of DNA, RNA, and various proteins that form chromosomes during cell division |
A chromatid is one of two genetically identical chromosome strands in which a chromosome splits longitudinally to prepare for cell division |
Composition |
Chromatin consists of DNA molecules wrapped around histone proteins, forming nucleosomes |
Chromatids are replicated copies of a single chromosome that join together at the centrosome |
Presence in cell cycle |
Chromatin is present throughout the entire cell cycle, and uncoil to become less condensed following telophase |
Chromatids are only present during the late stages of the cell cycle; they begin separating during metaphase and are at opposite poles of the cell during anaphase |
Function |
Chromatin acts the template for gene expression and allows for the proper packaging and organization of DNA (wrapped around histones) |
Chromatids primarily function in the distribution of genetic material during cell division |
Structure |
When not dividing, chromatin exists as a filamentos and loose structure in the nucleus |
Chromatids consists of one DNA molecule that is tightly coiled and condensed |
Chromatin Immunoprecipitation (ChIP)