What are the differences between CDS and cDNA?
Posted February 23, 2023
Answer
Basis of differentiation |
CDS (Coding Sequence) |
cDNA (Complementary DNA) |
Definition |
Is the coding region of RNA or DNA that codes for a particular protein |
Is a DNA sequence obtained from messenger RNA (mRNA) through the process of reverse transcription |
Composition |
Exons and 2 codons |
Complete mRNA and 2 untranslated regions (UTRs) |
Synthesis process |
Natural, every individual’s genomic DNA contains CDS |
Artificial, reverse transcription is used to synthesize cDNA from mRNA |
Untranslated regions |
Not included |
Included |
Use of reverse transcriptase |
Not used |
Used |
Additional resources
CDS Annotation in Full-Length cDNA Sequence