What are the applications of targeted resequencing?

One common targeted application using this method is the sequencing of the exome, which comprises the protein-coding regions of the genome. By focusing on the exome, researchers can identify genetic variations that are more likely to have functional consequences, such as mutations associated with diseases. Another targeted application involves sequencing specific genes of interest, often referred to as custom content. This approach allows researchers to investigate the genetic variations within particular genes known to be involved in specific biological processes or diseases. Additionally, targeted resequencing can also target specific regions within genes, such as regulatory elements or known functional domains. This allows for a more detailed examination of the genetic variation within these regions and its potential impact on gene function. In clinical diagnostics and pharmaceutical research, cost-effectiveness and rapid turnaround times are vital. Targeted sequencing offers a simplified and cost-efficient solution, allowing researchers to focus sequencing efforts on relevant genomic regions of interest.