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AAT Bioquest

What are the advantages of using microplate readers for the determination of binding affinity?

Posted May 14, 2024


Answer

These are some of the more significant advantages of using microplate readers for determining binding affinity:

  • Can test up to 3456 samples within minutes or even within seconds, minimizing operational time and saving on reagent costs
  • Deliver robust and reproducible results with minimal variability
  • Offer enhanced performance and sensitivity
  • Support upscaling processes with shorter evaluation times, smaller sample volumes and the ability to read multiple samples at once
  • Can be easily integrated into automated systems
  • Ideal platforms for integration in high-throughput facilities  
Additional resources

On the binding affinity of macromolecular interactions: daring to ask why proteins interact

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