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AAT Bioquest

What are the advantages of liposomes?

Posted October 2, 2024


Answer

Advantages of Liposomes include:

  • Liposomes are versatile and highly adaptable for different treatments due to their ability to carry both hydrophilic (water-soluble) and hydrophobic (fat-soluble) drugs.
  • Made up of natural phospholipids, liposomes are biocompatible and biodegradable, reducing the risk of harmful reactions in the body. 
  • Some liposomes, such as PEGylated liposomes, are capable of avoiding detection by the immune system, allowing them to stay in the bloodstream for longer periods. 
  • Liposomes can exploit the Enhanced Permeability and Retention (EPR) effect, which enables them to accumulate in tumor tissues for passive tumor targeting. 
  • Liposomes provide a protective barrier for unstable drugs, preventing their degradation before they reach the target site. 
  • Liposomes help reduce toxicity by focusing drug delivery to the target site and limiting exposure to non-target areas. 
Additional resources

Advances and Challenges of Liposome Assisted Drug Delivery

Cell Meter™ Intracellular Colorimetric Lipid Peroxidation (MDA) Assay Kit