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AAT Bioquest

What are the advantages of Illumina sequencing?

Posted February 9, 2024


Answer

There are various advantages of Illumina. These systems offer capacity, speed, and cost to carry out different sequencing requirements or laboratory needs. Illumina sequencing platforms offer high throughput, allowing the simultaneous sequencing of millions of DNA fragments in a single run. Additionally, illumina sequencing exhibits highly accurate base-by-base sequencing, effectively removing all errors specific to the sequence. This precision enables reliable base calling throughout the entire genome, even in challenging regions like repetitive sequences and homopolymers. Illumina systems are also suitable for various applications, including transcriptome analysis, targeted sequencing and entire genome sequencing. 

Additional resources

Limitations and errors of the Illumina method

Sanger Sequencing

MagaDye™ 535-ddGTP