What are labeled dextran conjugates used for?

Labeled dextran conjugates are used as long-term tracers for live cell studies in vitro and in vivo. Lysinated dextrans (which have primary amines on their surface) are useful for applications that require fixation and analysis. These conjugates are also useful for permeability assays, as they can assess the permeability of the blood-brain barrier to measure its function and integrity. Labeled dextran conjugates can be used in flow cytometry, and they can also be used as size markers, allowing scientists to calibrate and confirm the instrument’s accuracy. These conjugates can also be used to study the interactions between cells and glycan molecules. By conjugating a dextran to a specific glycan, scientists can study its functions. Lastly, these conjugates are used frequently in microscopy to visualize the distribution and intake of the conjugate in cells or tissues.