How does feedback inhibition work?

Feedback inhibition works by regulating metabolic pathways through the inhibition of unnecessary chemical reactions in an organism. This is performed by allosteric regulation, a process in which enzyme function is hindered by a molecule binding to an allosteric site on the enzyme, which is distinct from its active site. 

The regulatory mechanism is initiated when the substrate first binds to the enzyme, triggering a chain of events in which every product formed in the chain is used for subsequent steps in the pathway.  When an inhibitor molecule binds to an allosteric site of the enzyme, it changes the conformation of the enzyme, rendering it ineffective, which slows down or completely stops enzyme activity. 

Feedback inhibition plays an important role in modulating the end product of the reaction, thereby preventing excessive accumulation.