How does click chemistry work?
Posted April 10, 2024
Answer
Click reactions take place in a single container, generate minimal and harmless byproducts and are not influenced by water. They proceed irreversibly, producing a single product with precise specificity. Described as "spring-loaded," click reactions possess a robust driving force, ensuring efficient conversion to the desired product. Achieving this high energy state in the reactants can be challenging, often requiring methods such as utilizing light as a stimulus or using oxidation reactions.
Additional resources
Click Chemistry, a Powerful Tool for Pharmaceutical Sciences