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AAT Bioquest

How does Chimeric antigen receptor (CAR) T cell therapy work?

Posted July 9, 2024


Answer

Chimeric antigen receptor (CAR) T-cell therapy involves modifying T cells in the laboratory to enable them to recognize and attack cancer cells. This modification involves inserting a gene that encodes a chimeric antigen receptor. This receptor enables the T cells to recognize and bind to a specific antigen present on the surface of cancer cells. Once modified, these CAR T cells are reintroduced into the patient's body. Each CAR is designed to target a particular antigen unique to the type of cancer being treated.

Additional resources

CAR T Cell Therapy

PE/Texas Red® Anti-human CD4 Antibody *RPA-T4*

CD4 (Leu3, T4)