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AAT Bioquest

Do all cells release exosomes?

Posted July 21, 2023


Answer

No, not all cells release exosomes. Only cells that have an endomembrane system release exosomes. This includes most mammalian cells. Some cells such as dendritic cells, B cells, and mast cells of the immune system are found to release exosomes constitutively as a way to communicate with other cells in the body. The extent to which non-immune cells may release exosomes remains largely unknown.

Additional resources

The release and trans-synaptic transmission of Tau via exosomes

DiOC16(3) perchlorate [3,3-Dihexadecyloxacarbocyanine perchlorate]

DiR iodide [1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide]