Can gene transcription factors mutate?
Posted June 20, 2024
Answer
Yes, gene transcription factors can be mutated.
Transcription factors are proteins that bind to DNA sequences to regulate gene expression, which is critical for the synthesis of functional products that help in the proper functioning of cellular machinery.
When gene transcription factors mutate, the resultant dysregulation of gene expression can lead to various disorders and diseases from developmental aberrations to cancer.
Additional resources
Transcriptional Regulation and its Misregulation in Disease