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AAT Bioquest

What is the molecular weight (mw) of aldolase?

Posted June 21, 2018


Answer

160 kDa

 

Aldolase is present in all animal and plant tissue, and in most microorganisms. Class I aldolase is found in animal and higher plant tissue, while Class II aldolase is found only in prokaryotes and lower eukaryotes. There are three types of Class I aldolases: Type A (the major form) is found in muscle; Type B in liver and kidney; and Type C (plus some A) in brain. The molecular weight of aldolase is 160 kDa, which is equivalent of 160,000 g/mol. It exists as a homotetramer of four equal subunits of molecular weight 40 kDa.

Additional resources

Examination of the Dissociation of Multichain Proteins in Guanidine Hydrochloride by Membrane Osmometry