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AAT Bioquest

What is the function of the endoplasmic reticulum in the cell?

Posted August 19, 2021


Answer

The endoplasmic reticulum performs several functions in the cell including:

  • Production and synthesis of proteins
  • Transportation of proteins to another organelle such as the Golgi apparatus, plasma membrane or lysosomes
  • Formation of nuclear membrane during cell division
  • Synthesis of lipids, glycogen and steroids such as progesterone and testosterone
  • Increasing surface area for cellular reactions

There are two types of endoplasmic reticulum – smooth and rough. Both have slightly different function. The smooth endoplasmic reticulum is responsible for:

  • Synthesis of essential lipids such as cholesterol and phospholipids
  • Maintenance of calcium homeostasis
  • Metabolism of carbohydrates
  • Production and secretion of steroid hormones

The rough endoplasmic reticulum is responsible for:

  • Synthesis of proteins and enzymes
  • Protein folding
  • Protein sorting – Quality control
  • Formation of lysosomes
Additional resources

The endoplasmic reticulum: structure, function and response to cellular signaling

Endoplasmic Reticulum (ER)

Cell Navigator™ Live Cell Endoplasmic Reticulum (ER) Staining Kit *Blue Fluorescence*