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AAT Bioquest

Do cytokines cause pain?

Posted June 8, 2021


Answer

Not all cytokines cause pain. There are two types of cytokines – pro-inflammatory and anti-inflammatory cytokines. Only certain pro-inflammatory cytokines cause pain.

IL-1β, IL-6, and TNF-α are three of the most notable algesic pro-inflammatory cytokines that cause pain.

Additional resources

Cytokines, Inflammation and Pain