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AAT Bioquest

Are transferases involved in pyruvate conversion?

Posted September 8, 2021


Answer

Yes, transferases are involved in pyruvate conversion. Pyruvate conversion is catalyzed by the pyruvate dehydrogenase enzyme, which is part of the multienzyme Pyruvate dehydrogenase complex (PDC). This is a complex composed of three enzymes that catalyze the irreversible decarboxylation of pyruvate into acetyl-CoA.

Additional resources

Identification of the catalytic residues involved in the carboxyl transfer of pyruvate carboxylase

Amplite® Colorimetric Pyruvate Assay Kit