AssayWise Letters 2024, Vol. 13
Efficient and Versatile Nucleic Acid Labeling with Helixyte™ iFluor® Dyes: Enhancing Molecular Biology Applications
Nucleic acid labeling is a fundamental technique in molecular biology, enabling the detection, tracking, and analysis of DNA and RNA. While traditional methods have often posed challenges in terms of efficiency and consistency, the Helixyte™ iFluor® Nucleic Acid Labeling Dyes offer a direct, non-enzymatic…
Nucleic acid labeling is a fundamental technique in molecular biology, enabling the detection, tracking, and analysis of DNA and RNA. While traditional methods have often posed challenges in terms of efficiency and consistency, the Helixyte™ iFluor® Nucleic Acid Labeling Dyes offer a direct, non-enzymatic…
MitoDNA™ Red: A Powerful Tool for Labeling and Detection of mtDNA
Mitochondria are the only organelles in a cell that carry DNA apart from the nucleus. Mitochondrial DNA (mtDNA) plays a key role in cellular function, development, and disease. It contains the genetic information for synthesizing enzymes, transfer RNA (tRNA), and ribosomal RNA (rRNA). Mutations…
Mitochondria are the only organelles in a cell that carry DNA apart from the nucleus. Mitochondrial DNA (mtDNA) plays a key role in cellular function, development, and disease. It contains the genetic information for synthesizing enzymes, transfer RNA (tRNA), and ribosomal RNA (rRNA). Mutations…
Featured Article
SiRNA labeling and delivery into cells
Small interfering RNAs (siRNAs) are short double-stranded RNA molecules, ranging 20-25 base pairs in length. They are known to play a crucial role in gene regulation by modulating RNA interference (RNAi) pathway. The ability to control gene expression has made siRNAs a potential therapeutic target for diverse diseases. Delivering and visualizing the siRNAs, both in-vitro and in-vivo, to gain insights into their uptake and understanding the mechanism of action requires development of labeling technology that can provide detection of small amounts of siRNAs. Fluorescent labeling of…
Small interfering RNAs (siRNAs) are short double-stranded RNA molecules, ranging 20-25 base pairs in length. They are known to play a crucial role in gene regulation by modulating RNA interference (RNAi) pathway. The ability to control gene expression has made siRNAs a potential therapeutic target for diverse diseases. Delivering and visualizing the siRNAs, both in-vitro and in-vivo, to gain insights into their uptake and understanding the mechanism of action requires development of labeling technology that can provide detection of small amounts of siRNAs. Fluorescent labeling of…
Exploring AAT Bioquest FastClick™ Reagents: A Versatile Solution for Bioorthogonal Labeling in Complex Biological Systems
FastClick™ reagents, developed by AAT Bioquest, offer a transformative approach to copper-catalyzed azide-alkyne cycloaddition (CuAAC), enhancing both the reaction yield and speed under significantly milder conditions. Traditional CuAAC reactions often require high copper concentrations,…
FastClick™ reagents, developed by AAT Bioquest, offer a transformative approach to copper-catalyzed azide-alkyne cycloaddition (CuAAC), enhancing both the reaction yield and speed under significantly milder conditions. Traditional CuAAC reactions often require high copper concentrations,…