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TSQ [N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide]

TSQ is a fluorescent zinc indicator with high sensitivity.

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of TSQ [N-(6-Methoxy-8-quinolyl)-p-toluenesulfonamide] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM304.525 µL1.523 mL3.045 mL15.226 mL30.453 mL
5 mM60.905 µL304.525 µL609.05 µL3.045 mL6.091 mL
10 mM30.453 µL152.263 µL304.525 µL1.523 mL3.045 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

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Spectrum

Citations

View all 5 citations: Citation Explorer
Iron free zinc oxide nanoparticles with ion-leaking properties disrupt intracellular ROS and iron homeostasis to induce ferroptosis
Authors: Zhang, Changping and Liu, Zixuan and Zhang, Yuhao and Ma, Liang and Song, Erqun and Song, Yang
Journal: Cell Death \& Disease (2020): 1--15
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation
Authors: Liu, Zixuan and Lv, Xuying and Xu, Lei and Liu, Xuting and Zhu, Xiangyu and Song, Erqun and Song, Yang
Journal: Particle and fibre toxicology (2020): 1--17
The role of nitric oxide synthase in an early phase Cd-induced acute cytotoxicity in MCF-7 cells
Authors: Zhong, Lingying and Wang, Lumei and Xu, Lurong and Liu, Qunlu and Jiang, Linlei and Zhi, Yuee and Lu, Wei and Zhou, Pei
Journal: Biological Trace Element Research (2015): 130--138
The role of nitric oxide synthase in an early phase Cd-induced acute cytotoxicity in MCF-7 cells
Authors: Zhong, Lingying and Wang, Lumei and Xu, Lurong and Liu, Qunlu and Jiang, Linlei and Zhi, Yuee and Lu, Wei and Zhou, Pei
Journal: Biological trace element research (2015): 130--138
The role of NOS-mediated ROS accumulation in an early phase Cu-induced acute cytotoxicity in MCF-7 cells
Authors: Zhong, Lingying and Wang, Lumei and Xu, Lurong and Liu, Qunlu and Jiang, Linlei and Zhi, Yuee and Lu, Wei and Zhou, Pei
Journal: Biometals (2015): 113--122

References

View all 36 references: Citation Explorer
Neurotoxic zinc translocation into hippocampal neurons is inhibited by hypothermia and is aggravated by hyperthermia after traumatic brain injury in rats
Authors: Suh SW, Frederickson CJ, Danscher G.
Journal: J Cereb Blood Flow Metab (2006): 161
In vivo measurement of presynaptic Zn2+ release during forebrain ischemia in rats
Authors: Kitamura Y, Iida Y, Abe J, Mifune M, Kasuya F, Ohta M, Igarashi K, Saito Y, Saji H.
Journal: Biol Pharm Bull (2006): 821
Histochemical and histofluorescence tracing of chelatable zinc in the developing mouse
Authors: Nitzan YB, Sekler I, Silverman WF.
Journal: J Histochem Cytochem (2004): 529
Abundance of zinc ions in synaptic terminals of mocha mutant mice: zinc transporter 3 immunohistochemistry and zinc sulphide autometallography
Authors: Stoltenberg M, Nejsum LN, Larsen A, Danscher G.
Journal: J Mol Histol (2004): 141
Method for identifying neuronal cells suffering zinc toxicity by use of a novel fluorescent sensor
Authors: Frederickson CJ, Burdette SC, Sensi SL, Weiss JH, Yin HZ, Balaji RV, Truong-Tran AQ, Bedell E, Prough DS, Lippard SJ.
Journal: J Neurosci Methods (2004): 79
Page updated on November 21, 2024

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Physical properties

Molecular weight

328.38

Solvent

DMSO

Spectral properties

Excitation (nm)

355

Emission (nm)

499

Storage, safety and handling

Certificate of OriginDownload PDF
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12352200

CAS

109628-27-5
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