TF2-HQKLVFFAK-TQ2 [TF2-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-TQ2]
TF2-HQKLVFFAK-TQ2 [TF2-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Lys-TQ2] has much stronger fluoresce upon protease cleavage than the commonly used FRET peptide MCA-HQKLVFFA (K-DNP), a secretase FRET peptide substrate. In addition, the fluorescence of TF2 has much longer wavelength fluorescence than MCA, minimalizing the interference caused by the sample autofluorescence.
Spectrum
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References
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Endosome and Lysosome Membrane Properties Functionally Link to γ-Secretase in Live/Intact Cells.
Authors: Houser, Mei C Q and Mitchell, Shane P C and Sinha, Priyanka and Lundin, Brianna and Berezovska, Oksana and Maesako, Masato
Journal: Sensors (Basel, Switzerland) (2023)
Authors: Houser, Mei C Q and Mitchell, Shane P C and Sinha, Priyanka and Lundin, Brianna and Berezovska, Oksana and Maesako, Masato
Journal: Sensors (Basel, Switzerland) (2023)
In-Depth Characterization of Endo-Lysosomal Aβ in Intact Neurons.
Authors: McKendell, Alec K and Houser, Mei C Q and Mitchell, Shane P C and Wolfe, Michael S and Berezovska, Oksana and Maesako, Masato
Journal: Biosensors (2022)
Authors: McKendell, Alec K and Houser, Mei C Q and Mitchell, Shane P C and Wolfe, Michael S and Berezovska, Oksana and Maesako, Masato
Journal: Biosensors (2022)
A novel synthetic derivative of biaryl guanidine as a potential BACE1 inhibitor, to treat Alzheimer's disease: In-silico, in-vitro and in-vivo evaluation.
Authors: Ali, Sayyad and Hassan Bin Asad, Muhammad Hassham and Javed, Muhammad Arslan and Javed, Tariq and Al-Kharaman, Yasser Msa and Latif, Muhammad and Mohsin, Sabeeh and Nawaz, Taufiq and Farid Hasan, Syed Muhammad and Iqbal, Jamshed and Babak, Borhan and Hussain, Izhar
Journal: Pakistan journal of pharmaceutical sciences (2022): 1339-1345
Authors: Ali, Sayyad and Hassan Bin Asad, Muhammad Hassham and Javed, Muhammad Arslan and Javed, Tariq and Al-Kharaman, Yasser Msa and Latif, Muhammad and Mohsin, Sabeeh and Nawaz, Taufiq and Farid Hasan, Syed Muhammad and Iqbal, Jamshed and Babak, Borhan and Hussain, Izhar
Journal: Pakistan journal of pharmaceutical sciences (2022): 1339-1345
Neuronal KCNQ2/3 channels are recruited to lipid raft microdomains by palmitoylation of BACE1.
Authors: Dai, Gucan
Journal: The Journal of general physiology (2022)
Authors: Dai, Gucan
Journal: The Journal of general physiology (2022)
Presenilin/γ-Secretase Activity Is Located in Acidic Compartments of Live Neurons.
Authors: Maesako, Masato and Houser, Mei C Q and Turchyna, Yuliia and Wolfe, Michael S and Berezovska, Oksana
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience (2022): 145-154
Authors: Maesako, Masato and Houser, Mei C Q and Turchyna, Yuliia and Wolfe, Michael S and Berezovska, Oksana
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience (2022): 145-154
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