logo
AAT Bioquest

Texas Red TCO *Single isomer*

The tetrazine-trans-cyclooctene (TCO) ligation constitutes a non-toxic biomolecule labeling method of unparalleled speed. A tetrazine-functionalized molecule reacts with a TCO-functionalized molecule, forming a stable conjugate via a dihydropyrazine moiety. This inverse electron demand cycloaddition reaction has gained popularity due to the potential for extremely fast cycloaddition kinetics with TCO as the dienophile. AAT Bioquest offers a group of tetrazine- and TCO-containing dyes for exploring various biological systems that can use this powerful click reaction. Texas Red-TCO can be readily used to label tetrazine-modified biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. It is widely used for labeling tetrazine-modified peptides, proteins and oligos etc.

Spectrum

Product family

NameExcitation (nm)Emission (nm)Extinction coefficient (cm -1 M -1)Quantum yieldCorrection Factor (260 nm)Correction Factor (280 nm)Correction Factor (565 nm)
Texas Red® hydrazide *Single Isomer*58660311600010.971, 0.9320.230.360.4472
Texas Red® cadaverine *Single Isomer*58660311600010.971, 0.9320.230.360.4472
Texas Red® maleimide *Single Isomer*58660311600010.971, 0.9320.230.360.4472
Texas Red® azide *Single Isomer*58660311600010.971, 0.9320.230.360.4472
Texas Red® alkyne *Single Isomer*58660311600010.971, 0.9320.230.360.4472
Texas Red-DHPE *CAS 187099-99-6*58660311600010.971, 0.9320.230.360.4472

References

View all 50 references: Citation Explorer
Conditionally Controlling Human TLR2 Activity via Trans-Cyclooctene Caged Ligands.
Authors: van de Graaff, Michel J and Oosenbrug, Timo and Marqvorsen, Mikkel H S and Nascimento, Clarissa R and de Geus, Mark A R and Manoury, Bénédicte and Ressing, Maaike E and van Kasteren, Sander I
Journal: Bioconjugate chemistry (2020): 1685-1692
Titanium coating with mussel inspired polymer and bio-orthogonal chemistry enhances antimicrobial activity against Staphylococcus aureus.
Authors: Czuban, Magdalena and Kulka, Michaël W and Wang, Lei and Koliszak, Anna and Achazi, Katharina and Schlaich, Christoph and Donskyi, Ievgen S and Di Luca, Mariagrazia and Mejia Oneto, Jose M and Royzen, Maksim and Haag, Rainer and Trampuz, Andrej
Journal: Materials science & engineering. C, Materials for biological applications (2020): 111109
Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-length Antibodies.
Authors: Nazarova, Lidia and Rafidi, Hanine and Mandikian, Danielle and Ferl, Gregory Z and Koerber, James T and Davies, Christopher W and Ulufatu, Sheila and Ho, Jason and Lau, Jeffrey and Yu, Shang-Fan and Ernst, James and Sadowsky, Jack D and Boswell, C Andrew
Journal: Molecular cancer therapeutics (2020): 1052-1058
Tetrazine Carbon Nanotubes for Pretargeted In Vivo "Click-to-Release" Bioorthogonal Tumour Imaging.
Authors: Li, He and Conde, João and Guerreiro, Ana and Bernardes, Gonçalo J L
Journal: Angewandte Chemie (International ed. in English) (2020)
A Pretargeted Imaging Strategy for Immune Checkpoint Ligand PD-L1 Expression in Tumor Based on Bioorthogonal Diels-Alder Click Chemistry.
Authors: Qiu, Lin and Tan, Hui and Lin, Qingyu and Si, Zhan and Mao, Wujian and Wang, Tingting and Fu, Zhequan and Cheng, Dengfeng and Shi, Hongcheng
Journal: Molecular imaging and biology (2020): 842-853
Page updated on November 21, 2024

Ordering information

Price
Unit size
Catalog Number899
Quantity
Add to cart

Additional ordering information

Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
InternationalSee distributors
Bulk requestInquire
Custom sizeInquire
Technical SupportContact us
Purchase orderSend to sales@aatbio.com
ShippingStandard overnight for United States, inquire for international
Request quotation

Physical properties

Molecular weight

815.01

Solvent

DMSO

Spectral properties

Correction Factor (260 nm)

0.23

Correction Factor (280 nm)

0.36

Correction Factor (565 nm)

0.4472

Extinction coefficient (cm -1 M -1)

1160001

Excitation (nm)

586

Emission (nm)

603

Quantum yield

0.971, 0.932

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12171501