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Statine *CAS 49642-07-1*

(3S,4S)-Statine is a novel amino acid of pepstatin, a low molecular weight inhibitor of acid proteases
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Physical properties
Molecular weight175.23
SolventDMF
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C)
UNSPSC12352200
CAS49642-07-1
Calculators

Common stock solution preparation

Table 1. Volume of DMF needed to reconstitute specific mass of Statine *CAS 49642-07-1* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM570.679 µL2.853 mL5.707 mL28.534 mL57.068 mL
5 mM114.136 µL570.679 µL1.141 mL5.707 mL11.414 mL
10 mM57.068 µL285.339 µL570.679 µL2.853 mL5.707 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

Mass (Calculate)Molecular weightVolume (Calculate)Concentration (Calculate)Moles
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References
View all 54 references: Citation Explorer
Drug (statine)-induced hepatitis
Authors: Lazebnik LB, Zvenigorodskaia LA, Khomeriki SG, Efremov LI, Cherkashova EA.
Journal: Eksp Klin Gastroenterol (2009): 110
Investigation of the synthetic route to pepstatin analogues by SPPS using O-protected and O-unprotected statine as building blocks
Authors: Cadicamo CD, Asante V, Abu Ammar M, Borelli C, Korting HC, Koksch B.
Journal: J Pept Sci (2009): 272
Atovaquone-statine "double-drugs" with high antiplasmodial activity
Authors: Romeo S, Parapini S, Dell'Agli M, Vaiana N, Magrone P, Galli G, Sparatore A, Taramelli D, Bosisio E.
Journal: ChemMedChem (2008): 418
A simple microscale method for determining the relative stereochemistry of statine units
Authors: Preciado A, Williams PG.
Journal: J Org Chem (2008): 9228
Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues
Authors: Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B.
Journal: Bioorg Med Chem (2008): 9471