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Salinomycin-BSA conjugate

Salinomycin is a polyether monocarboxylic acid produced by Streptomyces albus. It is used in the prevention of coccidiosis in poultry caused by E. necatrix, E. tenella, E. acervulina, E. brunette, E. maxima, and E. mivati. Salinomycin is active against certain Gram-positive bacteria, whereas Enterobacteriaceae are resistant. Salinomycin also has an inhibitory effect on Clostridium perfringens, thus the use of salinomycin leads to a decrease in the incidence of necrotic enteritis in broiler chickens. Salinomycin is considered as the marker residue and skin/fat as the target tissue. Salinomycin produces relatively low residue levels in the eggs compared with other polyether ionophores. Salinomycin-BSA conjugate is used for developing and screening Salinomycin antibodies. It is also an excellent reagent for quantifying Salinomycin by ELISA.

References

View all 15 references: Citation Explorer
Salinomycin Modulates the Expression of mRNAs and miRNAs Related to Stemness in Endometrial Cancer.
Authors: Talkowski, Karol and Kiełbasiński, Kamil and Peszek, Wojciech and Grabarek, Beniamin O and Boroń, Dariusz and Oplawski, Marcin
Journal: Current pharmaceutical biotechnology (2021): 317-326
Simultaneous immunodetection of ionophore antibiotics, salinomycin and narasin, in poultry products and milk.
Authors: Burkin, Maksim A and Galvidis, Inna A
Journal: Analytical methods : advancing methods and applications (2021): 1550-1558
Effect of Salinomycin on Expression Pattern of Genes Associated with Apoptosis in Endometrial Cancer Cell Line.
Authors: Kiełbasiński, Kamil and Peszek, Wojciech and Grabarek, Beniamin O and Boroń, Dariusz and Wierzbik-Strońska, Magdalena and Oplawski, Marcin
Journal: Current pharmaceutical biotechnology (2020): 1269-1277
Evaluation of Variances in VEGF-A-D and VEGFR-1-3 Expression in the Ishikawa Endometrial Cancer Cell Line Treated with Salinomycin and An-ti-Angiogenic/Lymphangiogenic Effect.
Authors: Kras, Piotr and Talkowski, Karol and Grabarek, Beniamin Oskar and Dziobek, Nina and Boroń, Dariusz and Oplawski, Marcin
Journal: Current pharmaceutical biotechnology (2020)
Combination of salinomycin and radiation effectively eliminates head and neck squamous cell carcinoma cells in vitro.
Authors: Gehrke, Thomas and Hackenberg, Stephan and Polat, Bülent and Wohlleben, Gisela and Hagen, Rudolf and Kleinsasser, Norbert and Scherzad, Agmal
Journal: Oncology reports (2018): 1991-1998
Page updated on October 30, 2024

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Physical properties

Molecular weight

N/A

Solvent

Water

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12171501