Purified Anti-human CD19 Antibody *HIB19*

HIB19 is an anti-human monoclonal antibody that recognizes the CD19 antigen. CD19 (also known as CVID3) is a 95 kD glycoprotein that is located on the surface of cells like stem cells, dendritic cells and B cells. In certain organisms, CD19 promotes release of sequestered calcium ion into cytosol, plays a role in the upregulation of phosphatidylinositol 3-kinase activity and acts to positively regulate protein kinase B signaling. In addition, it is a member of critical cellular pathways, for example, the antigen receptor-mediated signaling pathway and B cell receptor signaling pathway. From a research standpoint, it is of biological interest due to its association with key macromolecules/ligands such as lyn. CD19 is a very popular antibody target, with over 36000 publications in the last decade. CD19 is often used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of immunology and costimulatory molecules. This antibody was purified through affinity chromatography.

Page updated on November 21, 2024