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Protonex™ Red 780 AM *Cell-Permeable*

Protonex™ Red 780 AM is the cell-permeable version of Protonex™ Red 780. Protonex™ Red 780 dye works by changing its fluorescence intensity depending on the pH of the environment. Protonex™ Red 780 is minimally fluorescent at a basic pH and maximally fluorescent at an acidic pH. When Protonex™ Red 780 is bound to an acidic intracellular target, it becomes highly fluorescent and emits near-infrared light when excited by a red laser. By measuring the fluorescence intensity of Protonex™ Red 780, one can label or monitor the acidic intracellular targets in live cells.

Spectrum

Product family

NameExcitation (nm)Emission (nm)
Protonex™ Red 670 AM *Cell-Permeable*643660
Protonex™ Red 780 acid748769

References

View all 50 references: Citation Explorer
mOrange2, a Genetically Encoded, pH Sensitive Fluorescent Protein, is an Alternative to BCECF-AM to Measure Intracellular pH to Determine NHE3 and DRA Activity.
Authors: Sarker, Rafiquel and Tse, Chung Ming and Lin, Ruxian and McNamara, George and Singh, Varsha and Donowitz, Mark
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology (2022): 39-49
Effects of Diluent pH on Enrichment and Performance of Dairy Goat X/Y Sperm.
Authors: He, Qifu and Wu, Shenghui and Huang, Ming and Wang, Ying and Zhang, Kang and Kang, Jian and Zhang, Yong and Quan, Fusheng
Journal: Frontiers in cell and developmental biology (2021): 747722
Intracellular pH regulation in mantle epithelial cells of the Pacific oyster, Crassostrea gigas.
Authors: Ramesh, Kirti and Hu, Marian Y and Melzner, Frank and Bleich, Markus and Himmerkus, Nina
Journal: Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology (2020): 691-700
Altered Degranulation and pH of Neutrophil Phagosomes Impacts Antimicrobial Efficiency in Cystic Fibrosis.
Authors: Hayes, Elaine and Murphy, Mark P and Pohl, Kerstin and Browne, Niall and McQuillan, Karen and Saw, Le Er and Foley, Clare and Gargoum, Fatma and McElvaney, Oliver J and Hawkins, Padraig and Gunaratnam, Cedric and McElvaney, Noel G and Reeves, Emer P
Journal: Frontiers in immunology (2020): 600033
Importance of measuring endolysosome, cytosolic, and extracellular pH in understanding the pathogenesis of and possible treatments for glioblastoma multiforme.
Authors: Halcrow, Peter and Khan, Nabab and Datta, Gaurav and Ohm, Joyce E and Chen, Xuesong and Geiger, Jonathan D
Journal: Cancer reports (2019)
Page updated on November 21, 2024

Ordering information

Price
Unit size
Catalog Number21186
Quantity
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Physical properties

Molecular weight

798.89

Solvent

DMSO

Spectral properties

Excitation (nm)

748

Emission (nm)

769

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12352200