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MQAE [N-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide]

A chloride indicator that has the fluorescence dependent of chloride concentration. Its fluorescence is quenched by chloride through collision quenching.

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of MQAE [N-(Ethoxycarbonylmethyl)-6-methoxyquinolinium bromide] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM306.57 µL1.533 mL3.066 mL15.328 mL30.657 mL
5 mM61.314 µL306.57 µL613.14 µL3.066 mL6.131 mL
10 mM30.657 µL153.285 µL306.57 µL1.533 mL3.066 mL

Molarity calculator

Enter any two values (mass, volume, concentration) to calculate the third.

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Spectrum

Citations

View all 1 citations: Citation Explorer
Lotus Leaf Alkaloid Extract Displays Sedative--Hypnotic and Anxiolytic Effects through GABAA Receptor
Authors: Yan, Ming-Zhu and Chang, Qi and Zhong, Yu and Xiao, Bing-Xin and Feng, Li and Cao, Fang-Rui and Pan, Rei-Le and Zhang, Ze-Sheng and Liao, Yong-Hong and Liu, Xin-Min
Journal: Journal of agricultural and food chemistry (2015): 9277--9285

References

View all 27 references: Citation Explorer
Chloride and bicarbonate have similar affinities to the intestinal anion exchanger DRA (down regulated in adenoma)
Authors: Lamprecht G, Schaefer J, Dietz K, Gregor M.
Journal: Pflugers Arch (2006): 307
Reversal effect of haloperidol on doxorubicin resistance and chloride channel inhibition in erythroleukemic cell K562/Dox
Authors: Zhou JH, Wu DZ.
Journal: Zhonghua Zhong Liu Za Zhi (2005): 81
On membrane motor activity and chloride flux in the outer hair cell: lessons learned from the environmental toxin tributyltin
Authors: Song L, Seeger A, Santos-Sacchi J.
Journal: Biophys J (2005): 2350
Measurement of halide efflux from cultured and primary airway epithelial cells using fluorescence indicators
Authors: Munkonge F, Alton EW, Andersson C, Davidson H, Dragomir A, Edelman A, Farley R, Hjelte L, McLachlan G, Stern M, Roomans GM.
Journal: J Cyst Fibros (2004): 171
Cell volume response to hyposmotic shock and elevated cAMP in bovine trabecular meshwork cells
Authors: Srinivas SP, Maertens C, Goon LH, Goon L, Satpathy M, Yue BY, Droogmans G, Nilius B.
Journal: Exp Eye Res (2004): 15
Page updated on November 21, 2024

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Physical properties

Molecular weight

326.19

Solvent

DMSO

Spectral properties

Excitation (nm)

319

Emission (nm)

462

Storage, safety and handling

Certificate of OriginDownload PDF
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12352200

CAS

162558-52-3
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