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MM 1-43 [N-(3-Triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide] *CAS#: 149838-22-2*
MM 1-43 is the abbreviation of our Membrane Marker 1-43, chemically called N-(3-triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide. MM 1-43 is chemically the same molecule of FM 1-43. In literature this membrane marker is also called "FM 1-43" (FM® is the trademark of Molecular Probes). It is a water-soluble membrane probe that belongs to the styryl dye family. It is widely used in cell biology and neurobiology since it has minimal toxicity to cells. MM 1-43 is virtually non-fluorescent in aqueous medium and strongly fluorescent upon binding to membrane. It is efficiently excited with standard fluorescein optical filters, and exhibits an intense fluorescent signal when associated with the plasma membrane. MM 1-43 has frequently been used to quantify exocytosis in neurons. Fluorescence imaging using MM 1-43 and related styryl dyes has provided invaluable insights into presynaptic function of synapses in culture preparations.
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Common stock solution preparation
Table 1. Volume of Water needed to reconstitute specific mass of MM 1-43 [N-(3-Triethylammoniumpropyl)-4-(4-(dibutylamino)styryl)pyridinium dibromide] *CAS#: 149838-22-2* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
| 0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
| 1 mM | 163.522 µL | 817.608 µL | 1.635 mL | 8.176 mL | 16.352 mL |
| 5 mM | 32.704 µL | 163.522 µL | 327.043 µL | 1.635 mL | 3.27 mL |
| 10 mM | 16.352 µL | 81.761 µL | 163.522 µL | 817.608 µL | 1.635 mL |
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References
View all 27 references: Citation Explorer
Palytoxin-induced effects on partial reactions of the Na,K-ATPase
Authors: Harmel N, Apell HJ.
Journal: J Gen Physiol (2006): 103
Authors: Harmel N, Apell HJ.
Journal: J Gen Physiol (2006): 103
Electrogenic partial reactions of the gastric H,K-ATPase
Authors: Diller A, Vagin O, Sachs G, Apell HJ.
Journal: Biophys J (2005): 3348
Authors: Diller A, Vagin O, Sachs G, Apell HJ.
Journal: Biophys J (2005): 3348
Effective gating charge of ion channels induced by toxin syringomycin E in lipid bilayers
Authors: Schagina LV, Gurnev PA, Takemoto JY, Malev VV.
Journal: Bioelectrochemistry (2003): 21
Authors: Schagina LV, Gurnev PA, Takemoto JY, Malev VV.
Journal: Bioelectrochemistry (2003): 21
Effect of dipole modifiers on the kinetics of sensitized photoinactivation of gramicidin channels in bilayer lipid membranes
Authors: Antonenko YN, Rokitskaya TI, Kotova EA.
Journal: Membr Cell Biol (1999): 111
Authors: Antonenko YN, Rokitskaya TI, Kotova EA.
Journal: Membr Cell Biol (1999): 111
Hofmeister effects of anions on the kinetics of partial reactions of the Na+,K+-ATPase
Authors: Ganea C, Babes A, Lupfert C, Grell E, Fendler K, Clarke RJ.
Journal: Biophys J (1999): 267
Authors: Ganea C, Babes A, Lupfert C, Grell E, Fendler K, Clarke RJ.
Journal: Biophys J (1999): 267
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