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Methylene Blue NHS Ester

Methylene Blue (MB) is widely used as a redox indicator in nucleic acid research. Methylene Blue NHS Ester is an excellent building block for preparing MB-labeled nucleic acid probes from amino-modified oligonucleotides. MB is also a well-known photosensitizer used in photodynamic therapy (PDT) and investigated for the topical treatment of various skin infections via PDT modality. It is a common biological stain, commonly used in medical laboratories to stain cells and tissues for microscopic examination. It can help visualize cellular structures and identify abnormalities. In addition, MB has been studied for its potential role in treating neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Some research suggests it might have a protective effect on neurons and mitochondrial function.

Spectrum

References

View all 13 references: Citation Explorer
Hydrogel Nanocomposite Towards Optical Sensing of Spermine in Biomedical and Real-Life Food Samples and Remediation of Toxic Dyes from Wastewater.
Authors: Biswakarma, Dipen and Dey, Nilanjan and Bhattacharya, Santanu
Journal: Langmuir : the ACS journal of surfaces and colloids (2023): 11610-11620
Controlled and Selective Photo-oxidation of Amyloid-β Fibrils by Oligomeric p-Phenylene Ethynylenes.
Authors: Fanni, Adeline M and Okoye, Daniel and Monge, Florencia A and Hammond, Julia and Maghsoodi, Fahimeh and Martin, Tye D and Brinkley, Gabriella and Phipps, M Lisa and Evans, Deborah G and Martinez, Jennifer S and Whitten, David G and Chi, Eva Y
Journal: ACS applied materials & interfaces (2022): 14871-14886
Control of Probe Density at DNA Biosensor Surfaces Using Poly(l-lysine) with Appended Reactive Groups.
Authors: Movilli, Jacopo and Rozzi, Andrea and Ricciardi, Roberto and Corradini, Roberto and Huskens, Jurriaan
Journal: Bioconjugate chemistry (2018): 4110-4118
Effects of polymers on the properties of hydrogels constructed using sodium deoxycholate and amino acid.
Authors: Guo, Yi and Wang, Ruijin and Shang, Yazhuo and Liu, Honglai
Journal: RSC advances (2018): 8699-8708
Tunable Signal-Off and Signal-On Electrochemical Cisplatin Sensor.
Authors: Wu, Yao and Lai, Rebecca Y
Journal: Analytical chemistry (2017): 9984-9989
Page updated on November 16, 2024

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Catalog Number830
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Physical properties

Molecular weight

538.96

Solvent

DMSO

Spectral properties

Absorbance (nm)

662

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
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