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Methylene Blue Alkyne

Methylene Blue (MB) is widely used as a redox indicator in nucleic acid research. Methylene Blue Alkyne is an excellent building block for preparing MB-labeled nucleic acid probes from azido-modified oligonucleotides, including picolyl azide-modified oligonucleotides via the well-known click chemistry. MB is also a well-known photosensitizer used in photodynamic therapy (PDT) and investigated for the topical treatment of various skin infections via PDT modality. It is a common biological stain, commonly used in medical laboratories to stain cells and tissues for microscopic examination. It can help visualize cellular structures and identify abnormalities. In addition, MB has been studied for its potential role in treating neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Some research suggests it might have a protective effect on neurons and mitochondrial function.

Spectrum

References

View all 50 references: Citation Explorer
[Retrospective analysis of BI-RADS 4 and 5 lesions additionally detected by breast MRI].
Authors: Jiang, L and Gao, J Y and Xu, Z J and He, S R and Hua, B
Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] (2023): 100-106
Preoperative localization of sentinel lymph nodes using percutaneous contrast-enhanced ultrasonography in patients with breast cancer.
Authors: Xu, Yi-Lin and Liu, Xue-Jing and Zhu, Ying and Lu, Hong
Journal: Gland surgery (2022): 369-377
Pseudoreticulocytosis by the ADVIA 2120 Hematology Analyzer and Other Hematologic Changes in a Cynomolgus Macaque (Macaca fascicularis) With Malaria.
Authors: Sharma, Diya and Priest, Heather and Wilcox, Angela
Journal: Toxicologic pathology (2022): 684-692
Dataset of multiple methodology characterization of an illite-kaolinite clay mineral for the purpose of using it as ceramic membrane supports.
Authors: Elgamouz, Abdelaziz and Tijani, Najib and Shehadi, Ihsan and Hasan, Kamrul and Al-Farooq Kawam, Mohamad
Journal: Data in brief (2020): 105300
Disposal of the large volume of sputum positive for Mycobacterium tuberculosis by using microwave sterilisation technology as an alternative to traditional autoclaving in a tertiary respiratory care hospital in Delhi, India.
Authors: Myneedu, Vithal Prasad and Aggarwal, Amit
Journal: Infection prevention in practice (2020): 100072
Page updated on November 16, 2024

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Physical properties

Molecular weight

492.52

Solvent

DMSO

Spectral properties

Absorbance (nm)

662

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
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