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Metal Fluor™ Zn-520, Potassium Salt
Metal Fluor™ Zn-520 is designed for detection of higher zinc ion concentrations that are present in synaptic vesicles and released in response to electrical stimulation or excitotoxic agonists (0.05-50 µM) with minimal interfering calcium sensitivity. Metal Fluor™ Zn-520 has shown great fluorescence enhancement upon binding zinc ion (>250 folds). This cell-impermeant zinc ion indicator is useful for detecting extracellular zinc ion.
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Common stock solution preparation
Table 1. Volume of Water needed to reconstitute specific mass of Metal Fluor™ Zn-520, Potassium Salt to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
| 0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
| 1 mM | 164.558 µL | 822.788 µL | 1.646 mL | 8.228 mL | 16.456 mL |
| 5 mM | 32.912 µL | 164.558 µL | 329.115 µL | 1.646 mL | 3.291 mL |
| 10 mM | 16.456 µL | 82.279 µL | 164.558 µL | 822.788 µL | 1.646 mL |
Molarity calculator
Enter any two values (mass, volume, concentration) to calculate the third.
| Mass (Calculate) | Molecular weight | Volume (Calculate) | Concentration (Calculate) | Moles | ||||
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Spectrum
Citations
View all 1 citations: Citation Explorer
Mitochondrial Dysfunction and Antioxidation Dyshomeostasis-Enhanced Tumor Starvation Synergistic Chemotherapy Achieved using a Metal--Organic Framework-Based Nano-Enzyme Reactor
Authors: Huo, Taotao and Leilei chen, and Nie, Huifang and Li, Wenshuai and Lin, Chenteng and Akhtar, Muhammad and Huang, Rongqin
Journal: ACS Applied Materials \& Interfaces (2022)
Authors: Huo, Taotao and Leilei chen, and Nie, Huifang and Li, Wenshuai and Lin, Chenteng and Akhtar, Muhammad and Huang, Rongqin
Journal: ACS Applied Materials \& Interfaces (2022)
References
View all 8 references: Citation Explorer
Zinquin identifies subcellular compartmentalization of zinc in cortical neurons. Relation to the trafficking of zinc and the mitochondrial compartment
Authors: Colvin RA, Laskowski M, Fontaine CP.
Journal: Brain Res (2006): 1
Authors: Colvin RA, Laskowski M, Fontaine CP.
Journal: Brain Res (2006): 1
S-Nitroso compounds interfere with zinc probing by Zinquin
Authors: Jansen S, Arning J, Dulcks T, Beyersmann D.
Journal: Anal Biochem (2004): 145
Authors: Jansen S, Arning J, Dulcks T, Beyersmann D.
Journal: Anal Biochem (2004): 145
Coordination and fluorescence of the intracellular Zn2+ probe [2-methyl-8-(4-toluenesulfonamido)-6-quinolyloxy]acetic acid (Zinquin A) in ternary Zn2+ complexes
Authors: Hendrickson KM, Geue JP, Wyness O, Lincoln SF, Ward AD.
Journal: J Am Chem Soc (2003): 3889
Authors: Hendrickson KM, Geue JP, Wyness O, Lincoln SF, Ward AD.
Journal: J Am Chem Soc (2003): 3889
Fluorescent detection of Zn(2+)-rich vesicles with Zinquin: mechanism of action in lipid environments
Authors: Snitsarev V, Budde T, Stricker TP, Cox JM, Krupa DJ, Geng L, Kay AR.
Journal: Biophys J (2001): 1538
Authors: Snitsarev V, Budde T, Stricker TP, Cox JM, Krupa DJ, Geng L, Kay AR.
Journal: Biophys J (2001): 1538
The synthesis and fluorescent properties of analogues of the zinc(II) specific fluorophore zinquin ester
Authors: Kimber MC, Mahadevan IB, Lincoln SF, Ward AD, Tiekink ER.
Journal: J Org Chem (2000): 8204
Authors: Kimber MC, Mahadevan IB, Lincoln SF, Ward AD, Tiekink ER.
Journal: J Org Chem (2000): 8204
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