iFluor® 594 Anti-human CD138 Antibody *MI15*

The MI15 monoclonal antibody reacts with human CD138, a 100 - 200 kD transmembrane protein typically expressed on the surface of b cells, plasma cells, epithelial cells and endothelial cells. CD138 is involved with important cellular pathways, in particular, the cytokine-mediated signaling pathway and canonical Wnt signaling pathway. Also, in certain organisms, it enhances extracellular exosome assembly and is a promoter of exosomal secretion. From a research standpoint, it is of biological interest due to its association with critical macromolecules/ligands such as Fibronectin. CD138 is a fairly uncommon antibody target, with a little more than 7000 publications in the last decade. Even still, CD138 is frequently used in flow cytometry applications as a phenotypic marker for differentiation of cell types, specifically in the study of cell motility/cytoskeleton/structure, cell biology and synaptic biology. This antibody was purified through affinity chromatography and conjugated to iFluor® 594 (ex/em = 588/604 nm). It is compatible with the 592 nm laser and 610/30 nm bandpass filter (for example, as in the Luminex Amnis ImageStream).

Page updated on December 17, 2024