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Hoechst 33342 maleimide
Hoechst 33342 maleimide is an excellent building block for developing site-specific nucleic acid probes. It can be readily conjugated to thiol-containing biomolecules (such as antibodies, peptides and thiol-modified oligos). Hoechst 33342 is a DNA-specific dye that binds to the minor groove of double-stranded DNA. It emits blue fluorescence when bound to DNA. Its excitation maximum is around 350 nm, and the emission maximum is approximately 460 nm. Its ability to readily penetrate live cell membranes makes it suitable for staining live cells. Hoechst 33342 is commonly used in fluorescence microscopy to visualize the nucleus of cells. It selectively stains the DNA in the cell nucleus and is often used in combination with other fluorochromes to study cell structure and dynamics. Hoechst 33342 is used for cell cycle analysis in flow cytometry. By staining DNA, it allows researchers to distinguish between different phases of the cell cycle, such as G1, S, and G2/M.
References
View all 50 references: Citation Explorer
AQP8 may affect glioma proliferation and growth by regulating GSK-3β phosphorylation and nuclear transport of β-catenin.
Authors: Cai, Ziling and Shen, Zihao and Zhao, Jing and Zhang, Hao and Guo, Zhen and Xia, Qingqian and Liang, Hang and Liu, Junnan and Tan, Lihao and Sheng, Huajun and Zhu, Shujuan
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuros (2023): 333-345
Authors: Cai, Ziling and Shen, Zihao and Zhao, Jing and Zhang, Hao and Guo, Zhen and Xia, Qingqian and Liang, Hang and Liu, Junnan and Tan, Lihao and Sheng, Huajun and Zhu, Shujuan
Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuros (2023): 333-345
EXOSC10 is a novel hepatocellular carcinoma prognostic biomarker: a comprehensive bioinformatics analysis and experiment verification.
Authors: Meng, Zhi-Yong and Fan, Yu-Chun and Zhang, Chao-Sheng and Zhang, Lin-Li and Wu, Tong and Nong, Min-Yu and Wang, Tian and Chen, Chuang and Jiang, Li-He
Journal: PeerJ (2023): e15860
Authors: Meng, Zhi-Yong and Fan, Yu-Chun and Zhang, Chao-Sheng and Zhang, Lin-Li and Wu, Tong and Nong, Min-Yu and Wang, Tian and Chen, Chuang and Jiang, Li-He
Journal: PeerJ (2023): e15860
Antimycin A induced apoptosis in HCT-116 colorectal cancer cells through the up- and downregulation of multiple signaling pathways.
Authors: Kabir, Syed Rashel and Islam, Tofazzal
Journal: Medical oncology (Northwood, London, England) (2022): 51
Authors: Kabir, Syed Rashel and Islam, Tofazzal
Journal: Medical oncology (Northwood, London, England) (2022): 51
Hypnea musciformis-mediated Ag/AgCl-NPs inhibit pathogenic bacteria, HCT-116 and MCF-7 cells' growth in vitro and Ehrlich ascites carcinoma cells in vivo in mice.
Authors: Ghose, Rita and Asaduzzaman, A K M and Hasan, Imtiaj and Kabir, Syed Rashel
Journal: IET nanobiotechnology (2022): 49-60
Authors: Ghose, Rita and Asaduzzaman, A K M and Hasan, Imtiaj and Kabir, Syed Rashel
Journal: IET nanobiotechnology (2022): 49-60
Role of ORAI calcium release-activated calcium modulator 1 (ORAI1) on neutrophil extracellular trap formation in dairy cows with subclinical hypocalcemia.
Authors: Zhang, Bingbing and Ma, Xinru and Loor, Juan J and Jiang, Qianming and Guo, Han and Zhang, Wei and Li, Ming and Lv, Xinquan and Yin, Yufeng and Wen, Jianan and Wang, Jingjing and Xu, Chuang and Yang, Wei
Journal: Journal of dairy science (2022): 3394-3404
Authors: Zhang, Bingbing and Ma, Xinru and Loor, Juan J and Jiang, Qianming and Guo, Han and Zhang, Wei and Li, Ming and Lv, Xinquan and Yin, Yufeng and Wen, Jianan and Wang, Jingjing and Xu, Chuang and Yang, Wei
Journal: Journal of dairy science (2022): 3394-3404
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