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Estradiol succinimidyl ester

Estradiol is an estrogen steroid hormone and the major female sex hormone. It is also called 17 beta-estradiol. Estradiol is involved in the regulation of the estrous and menstrual female reproductive cycles. It is responsible for the development of female secondary sexual characteristics and important in the development and maintenance of female reproductive tissues and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain. Though estradiol levels in males are much lower compared to those in females, estradiol has important roles in males as well. An estradiol test measures the amount of the hormone estradiol in your blood. It is also called an E2 test. An estradiol test has a number of clinically important applications. Estradiol succinimidyl ester is a convenient building block for developing estradiol conjugates and assays.

References

View all 30 references: Citation Explorer
Efficient Synthesis of Glutamate Peptide-Estradiol Conjugate for Imaging Estrogen Receptor-Positive Diseases.
Authors: Shih, Ming-Chi and Simon, Sergio Daniel and Jin, Zhiming and Gui, Yuan and Xu, Bohua and Xu, Zhihong and Rosado-de-Castro, Paulo Henrique and Silveira Braghirolli, Ana Maria and Barbosa da Fonseca, Lea Mirian and Inoue, Tomio and Yang, David J
Journal: BioMed research international (2018): 5208964
A Gold(III) Pincer Ligand Scaffold for the Synthesis of Binuclear and Bioconjugated Complexes: Synthesis and Anticancer Potential.
Authors: Bertrand, Benoît and O'Connell, Maria A and Waller, Zoë A E and Bochmann, Manfred
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) (2018): 3613-3622
Membrane-initiated estradiol signaling increases tyrosine hydroxylase promoter activity with ER alpha in PC12 cells.
Authors: Maharjan, Shreekrishna and Serova, Lidia I and Sabban, Esther L
Journal: Journal of neurochemistry (2010): 42-55
Bone selective effect of an estradiol conjugate with a novel tetracycline-derived bone-targeting agent.
Authors: Neale, Jason R and Richter, Natali B and Merten, Kevyn E and Taylor, K Grant and Singh, Sujan and Waite, Leonard C and Emery, Nicole K and Smith, Ned B and Cai, Jian and Pierce, William M
Journal: Bioorganic & medicinal chemistry letters (2009): 680-3
Picogram-detection of estradiol at an electrochemical immunosensor with a gold nanoparticle|Protein G-(LC-SPDP)-scaffold.
Authors: Liu, Xiaoqiang and Wong, Danny K Y
Journal: Talanta (2009): 1437-43
Page updated on December 17, 2024

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Catalog Number50545
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Physical properties

Molecular weight

456.50

Solvent

DMSO

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12171501
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Alternative formats