Deoxycholic acid-iFluor® 647 conjugate

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Additional ordering information

Telephone	1-800-990-8053
Fax	1-800-609-2943
Email	sales@aatbio.com
International	See distributors
Bulk request	Inquire
Custom size	Inquire
Shipping	Standard overnight for United States, inquire for international

Physical properties

Molecular weight	1253.63
Solvent	DMSO

Spectral properties

Correction Factor (260 nm)	0.03
Correction Factor (280 nm)	0.03
Correction Factor (656 nm)	0.0793
Extinction coefficient (cm ^-1 M ^-1)	250000¹
Excitation (nm)	656
Emission (nm)	670
Quantum yield	0.25¹

Storage, safety and handling

H-phrase	H303, H313, H333
Hazard symbol	XN
Intended use	Research Use Only (RUO)
R-phrase	R20, R21, R22
Storage	Freeze (< -15 °C); Minimize light exposure
UNSPSC	12171501

Overview SDS Protocol

Calculators

Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Deoxycholic acid-iFluor® 647 conjugate to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	79.768 µL	398.842 µL	797.684 µL	3.988 mL	7.977 mL
5 mM	15.954 µL	79.768 µL	159.537 µL	797.684 µL	1.595 mL
10 mM	7.977 µL	39.884 µL	79.768 µL	398.842 µL	797.684 µL

Molarity calculator

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Mass (Calculate)		Molecular weight		Volume (Calculate)		Concentration (Calculate)		Moles
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Spectrum

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Spectral properties

Correction Factor (260 nm)	0.03
Correction Factor (280 nm)	0.03
Correction Factor (656 nm)	0.0793
Extinction coefficient (cm ^-1 M ^-1)	250000¹
Excitation (nm)	656
Emission (nm)	670
Quantum yield	0.25¹

Images

Figure 1. Chemical structure for Deoxycholic acid-iFluor® 647 conjugate.

References

View all 50 references: Citation Explorer

Cationic nanoparticles self-assembled from amphiphilic chitosan derivatives containing poly(amidoamine) dendrons and deoxycholic acid as a vector for co-delivery of doxorubicin and gene.
Authors: Chen, Shanshan and Deng, Junjie and Zhang, Li-Ming
Journal: Carbohydrate polymers (2021): 117706

Deoxycholic Acid and Lithocholic Acid Alleviate Liver Injury and Inflammation in Mice with Klebsiella pneumoniae-Induced Liver Abscess and Bacteremia.
Authors: Zheng, Yahong and Yue, Chengcheng and Zhang, Hui and Chen, Haoran and Liu, Yanyan and Li, Jiabin
Journal: Journal of inflammation research (2021): 777-789

Efficacy and safety of injectable deoxycholic acid for submental fat reduction: a systematic review and meta-analysis of randomized controlled trials.
Authors: Cunha, Karin Soares and Lima, Flávia and Cardoso, Roberta Marques
Journal: Expert review of clinical pharmacology (2021): 383-397

Free Deoxycholic Acid Exacerbates Vascular Calcification in CKD through ER Stress-Mediated ATF4 Activation.
Authors: Miyazaki-Anzai, Shinobu and Masuda, Masashi and Shiozaki, Yuji and Keenan, Audrey L and Chonchol, Michel and Kremoser, Claus and Miyazaki, Makoto
Journal: Kidney360 (2021): 857-868

pH-sensitive chitosan-deoxycholic acid/alginate nanoparticles for oral insulin delivery.
Authors: Zhang, Ya-Wen and Tu, Ling-Lan and Tang, Zhan and Wang, Qiao and Zheng, Gao-Li and Yin, Li-Na
Journal: Pharmaceutical development and technology (2021): 1-10

Cholic acid and deoxycholic acid induce skeletal muscle atrophy through a mechanism dependent on TGR5 receptor.
Authors: Abrigo, Johanna and Gonzalez, Francisco and Aguirre, Francisco and Tacchi, Franco and Gonzalez, Andrea and Meza, María Paz and Simon, Felipe and Cabrera, Daniel and Arrese, Marco and Karpen, Saul and Cabello-Verrugio, Claudio
Journal: Journal of cellular physiology (2021): 260-272

Sodium alginate microencapsulation improves the short-term oral bioavailability of cannabidiol when administered with deoxycholic acid.
Authors: Majimbi, Maimuna and Brook, Emily and Galettis, Peter and Eden, Edward and Al-Salami, Hani and Mooranian, Armin and Al-Sallami, Hesham and Lam, Virginie and Mamo, John C L and Takechi, Ryusuke
Journal: PloS one (2021): e0243858

Evaluation of 1β-Hydroxylation of Deoxycholic Acid as a Non-Invasive Urinary Biomarker of CYP3A Activity in the Assessment of Inhibition-Based Drug-Drug Interaction in Healthy Volunteers.
Authors: Li, Xue-Qing and Thelingwani, Roslyn Stella and Bertilsson, Leif and Diczfalusy, Ulf and Andersson, Tommy B and Masimirembwa, Collen
Journal: Journal of personalized medicine (2021)

Design and synthesis of polyacrylic acid/deoxycholic acid-modified chitosan copolymer and a close inspection of human growth hormone-copolymer interactions: An experimental and computational study.
Authors: Khanmohammadi, Somayeh and Mehrnejad, Faramarz and Lotfi-Sousefi, Zahra and Yahyaei, Mohammad and Naderi-Manesh, Hossein
Journal: Colloids and surfaces. B, Biointerfaces (2021): 111956

Lesion reduction with intralesional deoxycholic acid in Dercum disease with radiographic evidence.
Authors: Rice, Shauna and Dalla Costa, Renata and Caravaglio, Joseph and Kourosh, A Shadi
Journal: JAAD case reports (2021): 73-75