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Congo Red-Biotin Conjugate

Congo Red has been used as a common qualitative staining method for the identification of amyloids in vitro and in tissue sections. Congo Red-Biotin is an excellent building block to develop Congo Red-based amyloid assays and tests. AAT Bioquest offers the largest collection of streptavidin conjugates that are paired with biotin probes for biological detections. The investigation of the amyloid formation is currently one of the most important tasks in the neurological field. Research in this area involves not only understanding how amyloidosis develops and how to prevent amyloid plaque formation but also investigating functional amyloids. In amyloidosis diseases, amyloids can be detected in the kidney, liver, brain and other human and animal organs. The development of neurodegenerative human diseases, such as Alzheimer’s disease and Parkinson’s disease, is probably the consequence of accumulation of insoluble amyloid plaques in the nerve tissue.

Spectrum

References

View all 13 references: Citation Explorer
Histological and immunohistochemical studies of the proximal caecum and caecal tonsils of quail (Coturnix coturnix japonica).
Authors: Yildiz, Mustafa and Aydemir, Isil and Kum, Sadiye and Eren, Ulker
Journal: Anatomia, histologia, embryologia (2019): 476-485
Ultrasensitive photoelectrochemical biosensing of multiple biomarkers on a single electrode by a light addressing strategy.
Authors: Wang, Juan and Liu, Zhihong and Hu, Chengguo and Hu, Shengshui
Journal: Analytical chemistry (2015): 9368-75
Neuroprotective effect of Liuwei Dihuang decoction on cognition deficits of diabetic encephalopathy in streptozotocin-induced diabetic rat.
Authors: Liu, Ji-ping and Feng, Liang and Zhang, Ming-hua and Ma, Dong-ying and Wang, Shu-yuan and Gu, Junfei and Fu, Qiang and Qu, Rong and Ma, Shi-ping
Journal: Journal of ethnopharmacology (2013): 371-81
Intrinsically disordered protein from a pathogenic mesophile Mycobacterium tuberculosis adopts structured conformation at high temperature.
Authors: Kumar, Niti and Shukla, Swati and Kumar, Sanjiv and Suryawanshi, Anju and Chaudhry, Uma and Ramachandran, Srinivasan and Maiti, Souvik
Journal: Proteins (2008): 1123-33
Metal ion-dependent, reversible, protein filament formation by designed beta-roll polypeptides.
Authors: Scotter, Andrew J and Guo, Meng and Tomczak, Melanie M and Daley, Margaret E and Campbell, Robert L and Oko, Richard J and Bateman, David A and Chakrabartty, Avijit and Sykes, Brian D and Davies, Peter L
Journal: BMC structural biology (2007): 63
Page updated on February 6, 2025

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Catalog Number23068
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Physical properties

Molecular weight

1008.11

Solvent

Water

Spectral properties

Absorbance (nm)

195

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure