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BSB [(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]
BSB is a cell-permeable fluorescent probe that specifically binds to and labels intracellular beta-amyloid aggregates both in vitro (Ki = 400 nM) and in vivo. It is useful as an antemortem diagnostic tool for animal models of Alzheimer's disease.
Calculators
Common stock solution preparation
Table 1. Volume of DMSO needed to reconstitute specific mass of BSB [(trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene] to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
| 0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
| 1 mM | 207.775 µL | 1.039 mL | 2.078 mL | 10.389 mL | 20.777 mL |
| 5 mM | 41.555 µL | 207.775 µL | 415.55 µL | 2.078 mL | 4.155 mL |
| 10 mM | 20.777 µL | 103.887 µL | 207.775 µL | 1.039 mL | 2.078 mL |
Molarity calculator
Enter any two values (mass, volume, concentration) to calculate the third.
| Mass (Calculate) | Molecular weight | Volume (Calculate) | Concentration (Calculate) | Moles | ||||
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References
View all 50 references: Citation Explorer
Focus on Molecules: Rod cGMP Phosphodiesterase Type 6
Authors: Ionita MA, Pittler SJ.
Journal: Exp Eye Res (2007): 1
Authors: Ionita MA, Pittler SJ.
Journal: Exp Eye Res (2007): 1
Translational regulation of the rod photoreceptor cGMP-phosphodiesterase: the role of the 5'- and 3'-untranslated regions
Authors: Piri N, Mendoza E, Shih J, Yamashita CK, Akhmedov NB, Farber DB.
Journal: Exp Eye Res (2006): 841
Authors: Piri N, Mendoza E, Shih J, Yamashita CK, Akhmedov NB, Farber DB.
Journal: Exp Eye Res (2006): 841
ANP-mediated cGMP signaling and phosphodiesterase inhibition in the rat cervical spinal cord
Authors: de Vente J, Markerink-van Ittersum M, Vles JS.
Journal: J Chem Neuroanat (2006): 263
Authors: de Vente J, Markerink-van Ittersum M, Vles JS.
Journal: J Chem Neuroanat (2006): 263
Enhancing cGMP in experimental progressive renal fibrosis: soluble guanylate cyclase stimulation vs. phosphodiesterase inhibition
Authors: Wang Y, Kramer S, Loof T, Martini S, Kron S, Kawachi H, Shimizu F, Neumayer HH, Peters H.
Journal: Am J Physiol Renal Physiol (2006): F167
Authors: Wang Y, Kramer S, Loof T, Martini S, Kron S, Kawachi H, Shimizu F, Neumayer HH, Peters H.
Journal: Am J Physiol Renal Physiol (2006): F167
Inhibition of cGMP-dependent protein kinase by the regulatory subunit of photoreceptor cGMP phosphodiesterase
Authors: Guo LW, Ruoho AE.
Journal: Neurosci Lett (2006): 252
Authors: Guo LW, Ruoho AE.
Journal: Neurosci Lett (2006): 252
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