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Bodi Fluor™ 581/591 C11 *Lipid Peroxidation Probe*

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Physical properties
Molecular weight504.43
SolventDMSO
Spectral properties
Excitation (nm)589
Emission (nm)597
Storage, safety and handling
H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22
StorageFreeze (< -15 °C); Minimize light exposure

OverviewpdfSDSpdfProtocol


Molecular weight
504.43
Excitation (nm)
589
Emission (nm)
597
Bodi Fluor™ 581/591 C11 is the same molecule as Bodipy 581/591 C11. It is a specific type of fluorescent dye used in various biological and biochemical applications. The "581/591" in the name refers to the wavelengths at which this particular Bodi Fluor dye exhibits maximum excitation (581 nm) and emission (591 nm). The "C11" part of the name typically indicates that the dye contains an 11-carbon aliphatic chain, which enhances its lipophilicity and makes it suitable for lipid-related studies. The lipophilic nature of the C11 moiety allows the dye to readily incorporate into cell membranes and other lipid-rich environments. One of the common applications of Bodi Fluor™ 581/591 C11 is to measure lipid peroxidation, a process involving the degradation of lipids through the action of reactive oxygen species (ROS). The dye's fluorescence changes with the oxidation state of lipids, and this unique property is exploited to assess lipid peroxidation levels in cells and tissues.

Calculators


Common stock solution preparation

Table 1. Volume of DMSO needed to reconstitute specific mass of Bodi Fluor™ 581/591 C11 *Lipid Peroxidation Probe* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.

0.1 mg0.5 mg1 mg5 mg10 mg
1 mM198.244 µL991.218 µL1.982 mL9.912 mL19.824 mL
5 mM39.649 µL198.244 µL396.487 µL1.982 mL3.965 mL
10 mM19.824 µL99.122 µL198.244 µL991.218 µL1.982 mL

Molarity calculator

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Spectrum


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spectrum

Spectral properties

Excitation (nm)589
Emission (nm)597

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References


View all 50 references: Citation Explorer
Acetyl-CoA Acetyltransferase 2 Confers Radioresistance by Inhibiting Ferroptosis in Esophageal Squamous Cell Carcinoma.
Authors: Heng, Jinghua and Li, Zhimao and Liu, Luxin and Zheng, Zhenyuan and Zheng, Yaqi and Xu, Xiue and Liao, Liandi and Xu, Hongyao and Huang, Hecheng and Li, Enmin and Xu, Liyan
Journal: International journal of radiation oncology, biology, physics (2023)
Histone acetyltransferase P300 deficiency promotes ferroptosis of vascular smooth muscle cells by activating the HIF-1α/HMOX1 axis.
Authors: Shi, Juan and Wang, Qun-Hui and Wei, Xiang and Huo, Bo and Ye, Jian-Nan and Yi, Xin and Feng, Xin and Fang, Ze-Min and Jiang, Ding-Sheng and Ma, Ming-Jia
Journal: Molecular medicine (Cambridge, Mass.) (2023): 91
General Approach to Identify, Assess, and Characterize Inhibitors of Lipid Peroxidation and Associated Cell Death.
Authors: Mallais, Melodie and Hanson, Carly S and Giray, Melanie and Pratt, Derek A
Journal: ACS chemical biology (2023): 561-571
Investigating ionizing radiation-induced changes in breast cancer cells using stimulated Raman scattering microscopy.
Authors: Allen, Christian Harry and Skillings, Robyn and Ahmed, Duale and Sanchez, Sarita Cuadros and Altwasser, Kaitlyn and Hilan, George and Willmore, William G and Chauhan, Vinita and Cassol, Edana and Murugkar, Sangeeta
Journal: Journal of biomedical optics (2023): 076501
MGST1 Expression Is Associated with Poor Prognosis, Enhancing the Wnt/β-Catenin Pathway via Regulating AKT and Inhibiting Ferroptosis in Gastric Cancer.
Authors: Li, Yaxian and Xu, Xin and Wang, Xiaodong and Zhang, Chaoyang and Hu, Asheng and Li, Yongxiang
Journal: ACS omega (2023): 23683-23694
Dimethyl fumarate protects against hepatic ischemia-reperfusion injury by alleviating ferroptosis via the NRF2/SLC7A11/HO-1 axis.
Authors: Qi, Debin and Chen, Peng and Bao, Haili and Zhang, Lei and Sun, Keyan and Song, Shaohua and Li, Tao
Journal: Cell cycle (Georgetown, Tex.) (2023): 818-828
Protective Effects of Querectin against MPP+-Induced Dopaminergic Neurons Injury via the Nrf2 Signaling Pathway.
Authors: Jiang, Yanyan and Xie, Guangming and Alimujiang, Aydos and Xie, Hongrong and Yang, Weiting and Yin, Feng and Huang, Dongya
Journal: Frontiers in bioscience (Landmark edition) (2023): 42
Ginsenoside Rg1 Suppresses Ferroptosis of Renal Tubular Epithelial Cells in Sepsis-induced Acute Kidney Injury via the FSP1-CoQ10-NAD(P)H Pathway.
Authors: Guo, Jun and Chen, Long and Ma, Min
Journal: Current medicinal chemistry (2023)
Metformin promotes ferroptosis and sensitivity to sorafenib in hepatocellular carcinoma cells via ATF4/STAT3.
Authors: Hu, Zongqiang and Zhao, Yingpeng and Li, Laibang and Jiang, Jie and Li, Wang and Mang, Yuanyi and Gao, Yang and Dong, Yun and Zhu, Jiashun and Yang, Chaomin and Ran, Jianghua and Li, Li and Zhang, Shengning
Journal: Molecular biology reports (2023)
Structural Analysis of Intracellular Lipid Radicals by LC/MS/MS Using a BODIPY-Based Profluorescent Nitroxide Probe.
Authors: Udo, Takumi and Matsuoka, Yuta and Takahashi, Masatomo and Izumi, Yoshihiro and Saito, Kota and Tazoe, Kaho and Tanaka, Moe and Naka, Hideto and Bamba, Takeshi and Yamada, Ken-Ichi
Journal: Analytical chemistry (2023): 4585-4591