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BOC-Statine [BOC-Sta(3S,4S)-OH] *CAS 58521-49-6*
(3S,4S)-Statine is a novel amino acid of pepstatin, a low molecular weight inhibitor of acid proteases. This BOC-Statine building lock is a very useful precursor for preparing protease-resistant peptide for pharmacetical application using the standard BOC chemistry.
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Common stock solution preparation
Table 1. Volume of DMF needed to reconstitute specific mass of BOC-Statine [BOC-Sta(3S,4S)-OH] *CAS 58521-49-6* to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
| 0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
| 1 mM | 363.187 µL | 1.816 mL | 3.632 mL | 18.159 mL | 36.319 mL |
| 5 mM | 72.637 µL | 363.187 µL | 726.375 µL | 3.632 mL | 7.264 mL |
| 10 mM | 36.319 µL | 181.594 µL | 363.187 µL | 1.816 mL | 3.632 mL |
Molarity calculator
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References
View all 54 references: Citation Explorer
Drug (statine)-induced hepatitis
Authors: Lazebnik LB, Zvenigorodskaia LA, Khomeriki SG, Efremov LI, Cherkashova EA.
Journal: Eksp Klin Gastroenterol (2009): 110
Authors: Lazebnik LB, Zvenigorodskaia LA, Khomeriki SG, Efremov LI, Cherkashova EA.
Journal: Eksp Klin Gastroenterol (2009): 110
Investigation of the synthetic route to pepstatin analogues by SPPS using O-protected and O-unprotected statine as building blocks
Authors: Cadicamo CD, Asante V, Abu Ammar M, Borelli C, Korting HC, Koksch B.
Journal: J Pept Sci (2009): 272
Authors: Cadicamo CD, Asante V, Abu Ammar M, Borelli C, Korting HC, Koksch B.
Journal: J Pept Sci (2009): 272
Atovaquone-statine "double-drugs" with high antiplasmodial activity
Authors: Romeo S, Parapini S, Dell'Agli M, Vaiana N, Magrone P, Galli G, Sparatore A, Taramelli D, Bosisio E.
Journal: ChemMedChem (2008): 418
Authors: Romeo S, Parapini S, Dell'Agli M, Vaiana N, Magrone P, Galli G, Sparatore A, Taramelli D, Bosisio E.
Journal: ChemMedChem (2008): 418
A simple microscale method for determining the relative stereochemistry of statine units
Authors: Preciado A, Williams PG.
Journal: J Org Chem (2008): 9228
Authors: Preciado A, Williams PG.
Journal: J Org Chem (2008): 9228
Design, synthesis and SAR of potent statine-based BACE-1 inhibitors: exploration of P1 phenoxy and benzyloxy residues
Authors: Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B.
Journal: Bioorg Med Chem (2008): 9471
Authors: Back M, Nyhlen J, Kvarnstrom I, Appelgren S, Borkakoti N, Jansson K, Lindberg J, Nystrom S, Hallberg A, Rosenquist S, Samuelsson B.
Journal: Bioorg Med Chem (2008): 9471
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