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BG Succinimidyl Ester

SNAP protein labeling system enables the specific, covalent attachment of virtually any molecule to a protein of interest. The SNAP-tag is a protein based on human O6-alkylguanine-DNA-alkyltransferase (hAGT). SNAP-tag substrates are fluorophores, biotin or beads conjugated to guanine or chloropyrimidine leaving groups via a benzyl linker. In the labeling reaction, the substituted benzyl group of the substrate is covalently attached to the SNAP-tag. BG Succinimidyl Ester is an amine-reactive building block for preparing of SNAP substrates from amine-containing labels or biological targets. BG Succinimidyl Ester building block facilities the development of various SNAP-tag substrates for labeling SNAP-tag fusion proteins for a wide range of biological applications.

References

View all 50 references: Citation Explorer
Photo-SNAP-tag, a Light-Regulated Chemical Labeling System.
Authors: Cleveland, Joseph D and Tucker, Chandra L
Journal: ACS chemical biology (2020)
The covalent SNAP tag for protein display quantification and low-pH protein engineering.
Authors: Jin, Wei and Madan, Bharat and Mussman, Brooklyn K and Hailemariam, Amen T and Fahad, Ahmed S and Wolfe, Jacy R and Kwon, Young Do and Zhang, Baoshan and Shapiro, Lawrence and Kwong, Peter D and DeKosky, Brandon J
Journal: Journal of biotechnology (2020): 50-56
Visualizing and Manipulating Biological Processes by Using HaloTag and SNAP-Tag Technologies.
Authors: Hoelzel, Conner A and Zhang, Xin
Journal: Chembiochem : a European journal of chemical biology (2020): 1935-1946
[Combined application of SNAP-tag and fluorescence technique in in-situ protein analysis].
Authors: Qiao, Qinglong and Zhou, Wei and Chen, Jie and Liu, Wenjuan and Miao, Lu and Yin, Wenting and Xu, Zhaochao
Journal: Se pu = Chinese journal of chromatography (2019): 872-877
A SNAP-tag fluorogenic probe mimicking the chromophore of the red fluorescent protein Kaede.
Authors: Jung, Kwan Ho and Fares, Matthew and Grainger, Leeann S and Wolstenholme, Charles H and Hou, Anna and Liu, Yu and Zhang, Xin
Journal: Organic & biomolecular chemistry (2019): 1906-1915
Page updated on November 12, 2024

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Catalog Number12564
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Physical properties

Molecular weight

481.47

Solvent

DMSO

Storage, safety and handling

H-phraseH303, H313, H333
Hazard symbolXN
Intended useResearch Use Only (RUO)
R-phraseR20, R21, R22

Storage

Freeze (< -15 °C); Minimize light exposure
UNSPSC12171501
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