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Beta-Estradiol-6-one 6-(O-carboxymethyloxime)
Ordering information
| Price | |
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| Unit Size | |
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Additional ordering information
| Telephone | 1-800-990-8053 |
| Fax | 1-800-609-2943 |
| sales@aatbio.com | |
| International | See distributors |
| Bulk request | Inquire |
| Custom size | Inquire |
| Shipping | Standard overnight for United States, inquire for international |
Physical properties
| Molecular weight | 460.62 |
| Solvent | DMSO |
Storage, safety and handling
| H-phrase | H303, H313, H333 |
| Hazard symbol | XN |
| Intended use | Research Use Only (RUO) |
| R-phrase | R20, R21, R22 |
| Storage | Freeze (< -15 °C); Minimize light exposure |
| UNSPSC | 12171501 |
| Overview |  SDSProtocol |
CAS 35048-47-6 | Molecular weight 460.62 |
Estradiol is an estrogen steroid hormone and the major female sex hormone. It is also called 17 beta-estradiol. Estradiol is involved in the regulation of the estrous and menstrual female reproductive cycles. It is responsible for the development of female secondary sexual characteristics and important in the development and maintenance of female reproductive tissues and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain. Though estradiol levels in males are much lower compared to those in females, estradiol has important roles in males as well. An estradiol test measures the amount of the hormone estradiol in your blood. It is also called an E2 test. An estradiol test has a number of clinically important applications. β-Estradiol-6-one 6-(O-carboxymethyloxime) is a convenient building block for developing estradiol conjugates and assays.
Calculators
Common stock solution preparation
Table 1. Volume of DMSO needed to reconstitute specific mass of Beta-Estradiol-6-one 6-(O-carboxymethyloxime) to given concentration. Note that volume is only for preparing stock solution. Refer to sample experimental protocol for appropriate experimental/physiological buffers.
| 0.1 mg | 0.5 mg | 1 mg | 5 mg | 10 mg | |
| 1 mM | 217.099 µL | 1.085 mL | 2.171 mL | 10.855 mL | 21.71 mL |
| 5 mM | 43.42 µL | 217.099 µL | 434.197 µL | 2.171 mL | 4.342 mL |
| 10 mM | 21.71 µL | 108.549 µL | 217.099 µL | 1.085 mL | 2.171 mL |
Molarity calculator
Enter any two values (mass, volume, concentration) to calculate the third.
| Mass (Calculate) | Molecular weight | Volume (Calculate) | Concentration (Calculate) | Moles | ||||
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Images
Figure 1. Chemical structure for ?-Estradiol-6-one 6-(O-carboxymethyloxime).
References
View all 50 references: Citation Explorer
Aloe/poloxamer hydrogel as an injectable β-estradiol delivery scaffold with multi-therapeutic effects to promote endometrial regeneration for intrauterine adhesion treatment.
Authors: Yao, Qing and Zheng, Ya-Wen and Lan, Qing-Hua and Wang, Li-Fen and Huang, Zhi-Wei and Chen, Rui and Yang, Yang and Xu, He-Lin and Kou, Longfa and Zhao, Ying-Zheng
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2020): 105316
Authors: Yao, Qing and Zheng, Ya-Wen and Lan, Qing-Hua and Wang, Li-Fen and Huang, Zhi-Wei and Chen, Rui and Yang, Yang and Xu, He-Lin and Kou, Longfa and Zhao, Ying-Zheng
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences (2020): 105316
Vitellogenins and choriogenins are biomarkers for monitoring Oryzias curvinotus juveniles exposed to 17 β - estradiol.
Authors: Dong, Zhongdian and Li, Xueyou and Huang, Shunkai and Zhang, Ning and Guo, Yusong and Wang, Zhongduo
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP (2020): 108800
Authors: Dong, Zhongdian and Li, Xueyou and Huang, Shunkai and Zhang, Ning and Guo, Yusong and Wang, Zhongduo
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP (2020): 108800
Effect of the side of ovulation on the uterine morphometry, blood flow, progesterone, estradiol, and nitric oxide during spontaneous and induced estrus in lactating dairy cows.
Authors: Abdelnaby, Elshymaa A and Abo El-Maaty, Amal M
Journal: Reproduction in domestic animals = Zuchthygiene (2020)
Authors: Abdelnaby, Elshymaa A and Abo El-Maaty, Amal M
Journal: Reproduction in domestic animals = Zuchthygiene (2020)
Smoking-Induced Inhibition of Number and Activity of Endothelial Progenitor Cells and Nitric Oxide in Males Were Reversed by Estradiol in Premenopausal Females.
Authors: Shao, Yijia and Luo, Liang and Ren, Zi and Guo, Jiayi and Xiao, Xingxing and Huang, Jiana and Zeng, Haitao and Zhan, Hong
Journal: Cardiology research and practice (2020): 9352518
Authors: Shao, Yijia and Luo, Liang and Ren, Zi and Guo, Jiayi and Xiao, Xingxing and Huang, Jiana and Zeng, Haitao and Zhan, Hong
Journal: Cardiology research and practice (2020): 9352518
Relationship between serum estradiol, cathepsin K, and N-telopeptide of type I collagen in female dogs.
Authors: Yamaguchi, Fumi and Nishi, Hiroshi and Kuramoto, Tomohide and Saitoh, Yasuo and Sogawa, Takeshi and Misumi, Kazuhiro and Fujiki, Makoto
Journal: Research in veterinary science (2020): 133-138
Authors: Yamaguchi, Fumi and Nishi, Hiroshi and Kuramoto, Tomohide and Saitoh, Yasuo and Sogawa, Takeshi and Misumi, Kazuhiro and Fujiki, Makoto
Journal: Research in veterinary science (2020): 133-138
Follicle-stimulating hormone and estradiol are associated with bone mineral density and risk of fractures in men with type 2 diabetes mellitus.
Authors: Jing, Yixuan and Wang, Xiaofeng and Yu, Jingjia and Wang, Xiaojing and Zhou, Yanman and Tao, Bei and Sun, Lihao and Liu, Jianmin and Zhao, Hongyan
Journal: Journal of diabetes (2020): 426-437
Authors: Jing, Yixuan and Wang, Xiaofeng and Yu, Jingjia and Wang, Xiaojing and Zhou, Yanman and Tao, Bei and Sun, Lihao and Liu, Jianmin and Zhao, Hongyan
Journal: Journal of diabetes (2020): 426-437
The effect of different estradiol levels on carotid artery distensibility during a long agonist IVF protocol.
Authors: Leppänen, Jonna and Randell, Kaisa and Schwab, Ursula and Pihlajamäki, Jussi and Keski-Nisula, Leea and Laitinen, Tomi and Heinonen, Seppo
Journal: Reproductive biology and endocrinology : RB&E (2020): 44
Authors: Leppänen, Jonna and Randell, Kaisa and Schwab, Ursula and Pihlajamäki, Jussi and Keski-Nisula, Leea and Laitinen, Tomi and Heinonen, Seppo
Journal: Reproductive biology and endocrinology : RB&E (2020): 44
Whole-Body Characterization of Estrogen Receptor Status in Metastatic Breast Cancer with 16α-18F-Fluoro-17β-Estradiol Positron Emission Tomography: Meta-Analysis and Recommendations for Integration into Clinical Applications.
Authors: Kurland, Brenda F and Wiggins, Jay R and Coche, Amandine and Fontan, Charlotte and Bouvet, Yann and Webner, Peter and Divgi, Chaitanya and Linden, Hannah M
Journal: The oncologist (2020)
Authors: Kurland, Brenda F and Wiggins, Jay R and Coche, Amandine and Fontan, Charlotte and Bouvet, Yann and Webner, Peter and Divgi, Chaitanya and Linden, Hannah M
Journal: The oncologist (2020)
17β-estradiol regulates prostaglandin E2 and F2α synthesis and function in endometrial explants of cattle.
Authors: Li, Qianru and Zhang, Shuangyi and Mao, Wei and Fu, Changqi and Shen, Yuan and Wang, Yijing and Liu, Bo and Cao, Jinshan
Journal: Animal reproduction science (2020): 106466
Authors: Li, Qianru and Zhang, Shuangyi and Mao, Wei and Fu, Changqi and Shen, Yuan and Wang, Yijing and Liu, Bo and Cao, Jinshan
Journal: Animal reproduction science (2020): 106466
U-Shaped Association of Plasma Testosterone, and no Association of Plasma Estradiol, with Incidence of Fractures in Men.
Authors: Yeap, Bu B and Alfonso, Helman and Chubb, S A Paul and Center, Jacqueline R and Beilin, Jonathan and Hankey, Graeme J and Almeida, Osvaldo P and Golledge, Jonathan and Norman, Paul E and Flicker, Leon
Journal: The Journal of clinical endocrinology and metabolism (2020)
Authors: Yeap, Bu B and Alfonso, Helman and Chubb, S A Paul and Center, Jacqueline R and Beilin, Jonathan and Hankey, Graeme J and Almeida, Osvaldo P and Golledge, Jonathan and Norman, Paul E and Flicker, Leon
Journal: The Journal of clinical endocrinology and metabolism (2020)