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AAT Bioquest

Anti-Thyroglobulin antibody *Mouse anti-human, monoclonal IgG1*

Thyroglobulin (TG) is a 660 kDa glycoprotein homodimer produced by follicular cells of the thyroid gland. It is used predominately within the thyroid gland as a precursor for the synthesis of thyroxine and triiodothyronine, both of which are thyroid hormones essential for regulating metabolism. Under normal physiological conditions, the levels of thyroglobulin circulating in the blood stream are low. However, in any thyroid pathology the level of thyroglobulin increases making it a promising biomarker for thyroid cancers and thyroid diseases such as Graves' disease. Anti-TG monoclonal antibodies are highly sensitive for the detection of human thyroglobulin immunogens. They can be used for a broad range of immunoassays such as chemiluminescent immunoassays (CLIA), and for IVD assay development.

Conjugation

We provide custom conjugation services for this antibody (eg. labeling of Anti-Thyroglobulin antibody *Mouse anti-human, monoclonal IgG1* with HRP). A list of available labels can be found in the table below:

AFAF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750
ProteinsHRP, Alkaline Phosphatase, Streptavidin
TandemsAPC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5
Small MoleculesBiotin
Traditional DyesFITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5
iFluor350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7
mFluorUV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780

For additional information about custom conjugations, please consult our services page here.
Page updated on December 17, 2024

Ordering information

Price
Unit size
50 ug
1 mg
Catalog Number
V100155V100156
Quantity
Add to cart

Additional ordering information

Telephone1-800-990-8053
Fax1-800-609-2943
Emailsales@aatbio.com
InternationalSee distributors
Bulk requestInquire
Custom sizeInquire
Technical SupportContact us
Purchase orderSend to sales@aatbio.com
ShippingStandard overnight for United States, inquire for international
Request quotation

Antibody properties

Other names
Hostmouse
Reactivityhuman
ApplicationELISA; CLIA

Storage, safety and handling

Intended useResearch Use Only (RUO)
Comparison between AAT Bioquest’s CLIA TG immunoassay and a competitor’s immunoassay: samples from donors were detected using different MAb combinations (A and B) from AAT Bioquest on a CLIA TG immunoassay, and compared to a competitor’s immunoassay. Results showed good correlation between both systems. The MAb combinations used are (capture-detection): Mab combination A: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 2); and Mab combination B: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 3).
Comparison between AAT Bioquest’s CLIA TG immunoassay and a competitor’s immunoassay: samples from donors were detected using different MAb combinations (A and B) from AAT Bioquest on a CLIA TG immunoassay, and compared to a competitor’s immunoassay. Results showed good correlation between both systems. The MAb combinations used are (capture-detection): Mab combination A: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 2); and Mab combination B: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 3).
Comparison between AAT Bioquest’s CLIA TG immunoassay and a competitor’s immunoassay: samples from donors were detected using different MAb combinations (A and B) from AAT Bioquest on a CLIA TG immunoassay, and compared to a competitor’s immunoassay. Results showed good correlation between both systems. The MAb combinations used are (capture-detection): Mab combination A: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 2); and Mab combination B: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 3).
Calibration curve for TG in chemiluminescence immunoassay (CLIA): all  MAbs  were  tested  in  pairs  as  capture  and  detection  antibodies  to  select  the best two-site MAb combinations for the development of a quantitative sandwich immunoassay. Detection  antibodies  were  labeled  with  horseradish peroxidase (HRP).The best selected MAb combinations for the development of  quantitative human  TG  immunoassays  are  (capture-detection): Mab combination A: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 2); and Mab combination B: Cat# V100155 (Clone 1) - Cat# V100155 (Clone 3).