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Anti-Insulin-like growth factor-binding protein 1(IGFBP1) antibody *Mouse anti-human, monoclonal IgG1*
Insulin-like growth factor-binding protein-1 (IGFBP-1), or placental protein 12 (PP12), belongs to a superfamily of IGFBPs that serve as carrier proteins for insulin-like growth factor (IGF-1). IGFBP-1 is synthesized and secreted by liver cells and by decidualized endometrial cells during pregnancy. It is expressed in liver, kidneys, and in amniotic fluid it is the most abundant IGFBP. IGFBP-1 binds equally to IGF-1 and IGF-II, and when phosphorylated IGFBP-1 exhibits higher binding affinities. In clinical biology, IGFBP-1 is a highly sensitive biomarker for the early diagnosis of premature rupture of fetal membranes (PROM) as the concentration of IGFBP-1 in amniotic fluid is 100 to 1000-fold higher than in human blood. Anti-IGFBP-1 monoclonal antibodies are highly sensitive for the detection of IGFBP-1 immunogens. They can be used for a broad range of immunoassays such as gold immunochromatography assays (GICA).
Conjugation
We provide custom conjugation services for this antibody (eg. labeling of Anti-Insulin-like growth factor-binding protein 1(IGFBP1) antibody *Mouse anti-human, monoclonal IgG1* with HRP). A list of available labels can be found in the table below:
For additional information about custom conjugations, please consult our services page here.
| AF | AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750 |
| Proteins | HRP, Alkaline Phosphatase, Streptavidin |
| Tandems | APC, APC/Cy7, APC/AF750, APC/iFluor™ 700, APC/iFluor™ 750, PE, PE/Cy5, PE/Cy7, PE/AF610, PE/AF700, PE/iFluor™ 594, PE/iFluor™ 647, PE/iFluor™ 700, PE/iFluor™ 750, PE/Texas Red®, PerCP, PerCP/Cy5.5 |
| Small Molecules | Biotin |
| Traditional Dyes | FITC (fluorescein), TRITC, PacBlue, PacOrange, Cy3, Cy5 |
| iFluor | 350, 405, 430, 450, 488, 514, 532, 546, 555, 560, 568, 594, 610, 633, 647, 660, 670, 680, 700, 710, 750, 790, 800, 810, 820, 840, 860, A7 |
| mFluor | UV375, UV460, Violet 450, Violet 500, Violet 510, Violet 540, Blue 570, Green 620, Red 700, Red 780 |
For additional information about custom conjugations, please consult our services page here.
Page updated on November 20, 2024
Safety data sheet